Pecci A - Search Results

1

Hemisuccinate of 21-hydroxy-6,19-epoxyprogesterone: a tissue-specific modulator of the glucocorticoid receptor.

Alvarez LD, Martí MA, Veleiro AS, Misico RI, Estrin DA, Pecci A, Burton G. Alvarez LD, et al. Among authors: pecci a. ChemMedChem. 2008 Dec;3(12):1869-77. doi: 10.1002/cmdc.200800256. ChemMedChem. 2008. PMID: 18985652

2

The glucocorticoid properties of the synthetic steroid pregna-1,4-diene-11beta-ol-3,20-dione (deltaHOP) are not entirely correlated with the steroid binding to the glucocorticoid receptor.

Vicent GP, Pecci A, Ghini AA, Piwien-Pilipuk G, Veleiro AS, Burton G, Lantos CP, Galigniana MD. Vicent GP, et al. Among authors: pecci a. Mol Cell Endocrinol. 1999 Mar 25;149(1-2):207-19. doi: 10.1016/s0303-7207(98)00205-6. Mol Cell Endocrinol. 1999. PMID: 10375032

3

6,19-Sulfur-bridged progesterone analogues with antiimmunosuppressive activity.

Veleiro AS, Pecci A, Monteserín MC, Baggio R, Garland MT, Lantos CP, Burton G. Veleiro AS, et al. Among authors: pecci a. J Med Chem. 2005 Sep 8;48(18):5675-83. doi: 10.1021/jm049266x. J Med Chem. 2005. PMID: 16134936

4

Exploring the molecular basis of action of the passive antiglucocorticoid 21-hydroxy-6,19-epoxyprogesterone.

Alvarez LD, Martí MA, Veleiro AS, Presman DM, Estrin DA, Pecci A, Burton G. Alvarez LD, et al. Among authors: pecci a. J Med Chem. 2008 Mar 13;51(5):1352-60. doi: 10.1021/jm800007w. Epub 2008 Feb 20. J Med Chem. 2008. PMID: 18284186

5

New lead compounds in the search for pure antiglucocorticoids and the dissociation of antiglucocorticoid effects.

Pecci A, Alvarez LD, Veleiro AS, Ceballos NR, Lantos CP, Burton G. Pecci A, et al. J Steroid Biochem Mol Biol. 2009 Feb;113(3-5):155-62. doi: 10.1016/j.jsbmb.2008.12.018. Epub 2009 Jan 9. J Steroid Biochem Mol Biol. 2009. PMID: 19167494 Review.

6

Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids.

Presman DM, Alvarez LD, Levi V, Eduardo S, Digman MA, Martí MA, Veleiro AS, Burton G, Pecci A. Presman DM, et al. Among authors: pecci a. PLoS One. 2010 Oct 11;5(10):e13279. doi: 10.1371/journal.pone.0013279. PLoS One. 2010. PMID: 20949009 Free PMC article.

7

Biological activity and ligand binding mode to the progesterone receptor of A-homo analogues of progesterone.

Alvarez LD, Dansey MV, Martí MA, Bertucci PY, Di Chenna PH, Pecci A, Burton G. Alvarez LD, et al. Among authors: pecci a. Bioorg Med Chem. 2011 Mar 1;19(5):1683-91. doi: 10.1016/j.bmc.2011.01.033. Epub 2011 Jan 22. Bioorg Med Chem. 2011. PMID: 21315613

8

27-Nor-Δ(4)-dafachronic acid is a synthetic ligand of Caenorhabditis elegans DAF-12 receptor.

Samaja GA, Castro O, Alvarez LD, Dansey MV, Escudero DS, Veleiro AS, Pecci A, Burton G. Samaja GA, et al. Among authors: pecci a. Bioorg Med Chem Lett. 2013 May 15;23(10):2893-6. doi: 10.1016/j.bmcl.2013.03.071. Epub 2013 Mar 28. Bioorg Med Chem Lett. 2013. PMID: 23570785

9

Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor.

Presman DM, Ogara MF, Stortz M, Alvarez LD, Pooley JR, Schiltz RL, Grøntved L, Johnson TA, Mittelstadt PR, Ashwell JD, Ganesan S, Burton G, Levi V, Hager GL, Pecci A. Presman DM, et al. Among authors: pecci a. PLoS Biol. 2014 Mar 18;12(3):e1001813. doi: 10.1371/journal.pbio.1001813. eCollection 2014 Mar. PLoS Biol. 2014. PMID: 24642507 Free PMC article.

10

The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy.

Orqueda AJ, Dansey MV, Español A, Veleiro AS, Bal de Kier Joffé E, Sales ME, Burton G, Pecci A. Orqueda AJ, et al. Among authors: pecci a. Biochem Pharmacol. 2014 Jun 15;89(4):526-35. doi: 10.1016/j.bcp.2014.04.006. Epub 2014 Apr 13. Biochem Pharmacol. 2014. PMID: 24735610 Free article.

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