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Page 1
Synthesis and pharmacological characterization of novel druglike corticotropin-releasing factor 1 antagonists.
Di Fabio R, St-Denis Y, Sabbatini FM, Andreotti D, Arban R, Bernasconi G, Braggio S, Blaney FE, Capelli AM, Castiglioni E, Di Modugno E, Donati D, Fazzolari E, Ratti E, Feriani A, Contini S, Gentile G, Ghirlanda D, Provera S, Marchioro C, Roberts KL, Mingardi A, Mattioli M, Nalin A, Pavone F, Spada S, Trist DG, Worby A. Di Fabio R, et al. Among authors: andreotti d. J Med Chem. 2008 Dec 11;51(23):7370-9. doi: 10.1021/jm800744m. J Med Chem. 2008. PMID: 18989952
Dihydropyrrole[2,3-d]pyridine derivatives as novel corticotropin-releasing factor-1 antagonists: mapping of the receptor binding pocket by in silico docking studies.
Di Fabio R, Arban R, Bernasconi G, Braggio S, Blaney FE, Capelli AM, Castiglioni E, Donati D, Fazzolari E, Ratti E, Feriani A, Contini S, Gentile G, Ghirlanda D, Sabbatini FM, Andreotti D, Spada S, Marchioro C, Worby A, St-Denis Y. Di Fabio R, et al. Among authors: andreotti d. J Med Chem. 2008 Nov 27;51(22):7273-86. doi: 10.1021/jm800743q. J Med Chem. 2008. PMID: 18975927
6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor.
Micheli F, Cavanni P, Andreotti D, Arban R, Benedetti R, Bertani B, Bettati M, Bettelini L, Bonanomi G, Braggio S, Carletti R, Checchia A, Corsi M, Fazzolari E, Fontana S, Marchioro C, Merlo-Pich E, Negri M, Oliosi B, Ratti E, Read KD, Roscic M, Sartori I, Spada S, Tedesco G, Tarsi L, Terreni S, Visentini F, Zocchi A, Zonzini L, Di Fabio R. Micheli F, et al. Among authors: andreotti d. J Med Chem. 2010 Jul 8;53(13):4989-5001. doi: 10.1021/jm100481d. J Med Chem. 2010. PMID: 20527970
A specific and direct comparison of the trifluoromethyl and pentafluoro sulfanyl groups on the selective dopamine D(3) antagonist 3-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-1-phenyl-3-azabicyclo[3.1.0]hexane template.
Micheli F, Andreotti D, Braggio S, Checchia A. Micheli F, et al. Among authors: andreotti d. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4566-8. doi: 10.1016/j.bmcl.2010.06.018. Epub 2010 Jun 8. Bioorg Med Chem Lett. 2010. PMID: 20573506
Discovery of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a novel clinical AMPA receptor positive modulator.
Ward SE, Harries M, Aldegheri L, Andreotti D, Ballantine S, Bax BD, Harris AJ, Harker AJ, Lund J, Melarange R, Mingardi A, Mookherjee C, Mosley J, Neve M, Oliosi B, Profeta R, Smith KJ, Smith PW, Spada S, Thewlis KM, Yusaf SP. Ward SE, et al. Among authors: andreotti d. J Med Chem. 2010 Aug 12;53(15):5801-12. doi: 10.1021/jm1005429. J Med Chem. 2010. PMID: 20614889 Clinical Trial.
Selective Inhibitors of G2019S-LRRK2 Kinase Activity.
Garofalo AW, Bright J, De Lombaert S, Toda AMA, Zobel K, Andreotti D, Beato C, Bernardi S, Budassi F, Caberlotto L, Gao P, Griffante C, Liu X, Mengatto L, Migliore M, Sabbatini FM, Sava A, Serra E, Vincetti P, Zhang M, Carlisle HJ. Garofalo AW, et al. Among authors: andreotti d. J Med Chem. 2020 Dec 10;63(23):14821-14839. doi: 10.1021/acs.jmedchem.0c01243. Epub 2020 Nov 16. J Med Chem. 2020. PMID: 33197196
Structure-guided design of antibacterials that allosterically inhibit DNA gyrase.
Thalji RK, Raha K, Andreotti D, Checchia A, Cui H, Meneghelli G, Profeta R, Tonelli F, Tommasi S, Bakshi T, Donovan BT, Howells A, Jain S, Nixon C, Quinque G, McCloskey L, Bax BD, Neu M, Chan PF, Stavenger RA. Thalji RK, et al. Among authors: andreotti d. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1407-1412. doi: 10.1016/j.bmcl.2019.03.029. Epub 2019 Mar 22. Bioorg Med Chem Lett. 2019. PMID: 30962087
Synthesis of novel 6-alpha and 6-beta-alkylcarbonylmethyl substituted penems.
Pentassuglia G, Tarzia G, Andreotti D, Bismara C, Carlesso R, Donati D, Gaviraghi G, Perboni A, Pezzoli A, Rossi T, et al. Pentassuglia G, et al. Among authors: andreotti d. J Antibiot (Tokyo). 1995 May;48(5):399-407. doi: 10.7164/antibiotics.48.399. J Antibiot (Tokyo). 1995. PMID: 7797442 Free article.
58 results