Mahuran D - Search Results

1

1-Deoxygalactonojirimycin-lysine hybrids as potent D-galactosidase inhibitors.

Steiner AJ, Schitter G, Stütz AE, Wrodnigg TM, Tarling CA, Withers SG, Fantur K, Mahuran D, Paschke E, Tropak M. Steiner AJ, et al. Among authors: mahuran d. Bioorg Med Chem. 2008 Dec 15;16(24):10216-20. doi: 10.1016/j.bmc.2008.10.054. Epub 2008 Oct 26. Bioorg Med Chem. 2008. PMID: 18996021 Free PMC article.

2

Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors.

Schitter G, Scheucher E, Steiner AJ, Stütz AE, Thonhofer M, Tarling CA, Withers SG, Wicki J, Fantur K, Paschke E, Mahuran DJ, Rigat BA, Tropak M, Wrodnigg TM. Schitter G, et al. Beilstein J Org Chem. 2010 Mar 1;6:21. doi: 10.3762/bjoc.6.21. Beilstein J Org Chem. 2010. PMID: 20502610 Free PMC article.

3

Fluorous iminoalditols: a new family of glycosidase inhibitors and pharmacological chaperones.

Schitter G, Steiner AJ, Pototschnig G, Scheucher E, Thonhofer M, Tarling CA, Withers SG, Fantur K, Paschke E, Mahuran DJ, Rigat BA, Tropak MB, Illaszewicz C, Saf R, Stütz AE, Wrodnigg TM. Schitter G, et al. Chembiochem. 2010 Sep 24;11(14):2026-33. doi: 10.1002/cbic.201000192. Chembiochem. 2010. PMID: 20715263 Free PMC article.

4

2-Acetamino-1,2-dideoxynojirimycin-lysine hybrids as hexosaminidase inhibitors.

Steiner AJ, Schitter G, Stütz AE, Wrodnigg TM, Tarling CA, Withers SG, Mahuran DJ, Tropak MB. Steiner AJ, et al. Tetrahedron Asymmetry. 2009 May 1;20(6-8):832-835. doi: 10.1016/j.tetasy.2009.02.015. Tetrahedron Asymmetry. 2009. PMID: 22328804 Free PMC article.

5

Rapid assembly of a library of lipophilic iminosugars via the thiol-ene reaction yields promising pharmacological chaperones for the treatment of Gaucher disease.

Goddard-Borger ED, Tropak MB, Yonekawa S, Tysoe C, Mahuran DJ, Withers SG. Goddard-Borger ED, et al. Among authors: mahuran dj. J Med Chem. 2012 Mar 22;55(6):2737-45. doi: 10.1021/jm201633y. Epub 2012 Mar 6. J Med Chem. 2012. PMID: 22360565 Free PMC article.

6

1-Deoxynojirimycins with dansyl capped N-substituents as probes for Morbus Gaucher affected cell lines.

Fröhlich RF, Furneaux RH, Mahuran DJ, Rigat BA, Stütz AE, Tropak MB, Wicki J, Withers SG, Wrodnigg TM. Fröhlich RF, et al. Carbohydr Res. 2010 Jul 2;345(10):1371-6. doi: 10.1016/j.carres.2010.04.015. Epub 2010 Apr 24. Carbohydr Res. 2010. PMID: 20471633 Free PMC article.

7

1-Deoxy-D-galactonojirimycins with dansyl capped N-substituents as β-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines.

Fröhlich RF, Furneaux RH, Mahuran DJ, Saf R, Stütz AE, Tropak MB, Wicki J, Withers SG, Wrodnigg TM. Fröhlich RF, et al. Carbohydr Res. 2011 Sep 6;346(12):1592-8. doi: 10.1016/j.carres.2011.05.010. Epub 2011 May 24. Carbohydr Res. 2011. PMID: 21645885 Free PMC article.

8

High-throughput screening for human lysosomal beta-N-Acetyl hexosaminidase inhibitors acting as pharmacological chaperones.

Tropak MB, Blanchard JE, Withers SG, Brown ED, Mahuran D. Tropak MB, et al. Among authors: mahuran d. Chem Biol. 2007 Feb;14(2):153-64. doi: 10.1016/j.chembiol.2006.12.006. Chem Biol. 2007. PMID: 17317569 Free PMC article.

9

Thioglycoligase-based assembly of thiodisaccharides: screening as beta-galactosidase inhibitors.

Kim YW, Chen HM, Kim JH, Müllegger J, Mahuran D, Withers SG. Kim YW, et al. Among authors: mahuran d. Chembiochem. 2007 Sep 3;8(13):1495-9. doi: 10.1002/cbic.200700263. Chembiochem. 2007. PMID: 17661304 Free PMC article. No abstract available.

10

Tailoring the specificity and reactivity of a mechanism-based inactivator of glucocerebrosidase for potential therapeutic applications.

Rempel BP, Tropak MB, Mahuran DJ, Withers SG. Rempel BP, et al. Angew Chem Int Ed Engl. 2011 Oct 24;50(44):10381-3. doi: 10.1002/anie.201103924. Epub 2011 Sep 13. Angew Chem Int Ed Engl. 2011. PMID: 21915968 No abstract available.

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