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Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL.
Kostenuik PJ, Nguyen HQ, McCabe J, Warmington KS, Kurahara C, Sun N, Chen C, Li L, Cattley RC, Van G, Scully S, Elliott R, Grisanti M, Morony S, Tan HL, Asuncion F, Li X, Ominsky MS, Stolina M, Dwyer D, Dougall WC, Hawkins N, Boyle WJ, Simonet WS, Sullivan JK. Kostenuik PJ, et al. Among authors: kurahara c. J Bone Miner Res. 2009 Feb;24(2):182-95. doi: 10.1359/jbmr.081112. J Bone Miner Res. 2009. PMID: 19016581 Free article.
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength.
Li X, Ominsky MS, Niu QT, Sun N, Daugherty B, D'Agostin D, Kurahara C, Gao Y, Cao J, Gong J, Asuncion F, Barrero M, Warmington K, Dwyer D, Stolina M, Morony S, Sarosi I, Kostenuik PJ, Lacey DL, Simonet WS, Ke HZ, Paszty C. Li X, et al. Among authors: kurahara c. J Bone Miner Res. 2008 Jun;23(6):860-9. doi: 10.1359/jbmr.080216. J Bone Miner Res. 2008. PMID: 18269310 Free article.
Heterologous expression of the adenosine A1 receptor in transgenic mouse retina.
Li N, Salom D, Zhang L, Harris T, Ballesteros JA, Golczak M, Jastrzebska B, Palczewski K, Kurahara C, Juan T, Jordan S, Salon JA. Li N, et al. Among authors: kurahara c. Biochemistry. 2007 Jul 17;46(28):8350-9. doi: 10.1021/bi700154h. Epub 2007 Jun 20. Biochemistry. 2007. PMID: 17580959
Regulation of T cell activation and tolerance by PDL2.
Zhang Y, Chung Y, Bishop C, Daugherty B, Chute H, Holst P, Kurahara C, Lott F, Sun N, Welcher AA, Dong C. Zhang Y, et al. Among authors: kurahara c. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11695-700. doi: 10.1073/pnas.0601347103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864790 Free PMC article.
Immune function in mice lacking the perforin gene.
Walsh CM, Matloubian M, Liu CC, Ueda R, Kurahara CG, Christensen JL, Huang MT, Young JD, Ahmed R, Clark WR. Walsh CM, et al. Among authors: kurahara cg. Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):10854-8. doi: 10.1073/pnas.91.23.10854. Proc Natl Acad Sci U S A. 1994. PMID: 7526382 Free PMC article.
25 results