Hayden RE - Search Results

1

Elevated FOSB-expression; a potential marker of valproate sensitivity in AML.

Khanim FL, Bradbury CA, Arrazi J, Hayden RE, Rye A, Basu S, MacWhannell A, Sawers A, Griffiths M, Cook M, Freeman S, Nightingale KP, Grimwade D, Falciani F, Turner BM, Bunce CM, Craddock C. Khanim FL, et al. Among authors: hayden re. Br J Haematol. 2009 Feb;144(3):332-41. doi: 10.1111/j.1365-2141.2008.07449.x. Epub 2008 Nov 22. Br J Haematol. 2009. PMID: 19036090 Free article. Clinical Trial.

2

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

Bradbury CA, Khanim FL, Hayden R, Bunce CM, White DA, Drayson MT, Craddock C, Turner BM. Bradbury CA, et al. Leukemia. 2005 Oct;19(10):1751-9. doi: 10.1038/sj.leu.2403910. Leukemia. 2005. PMID: 16121216

3

Combined bezafibrate and medroxyprogesterone acetate have efficacy without haematological toxicity in elderly and relapsed acute myeloid leukaemia (AML).

Murray JA, Khanim FL, Hayden RE, Craddock CF, Holyoake TL, Jackson N, Lumley M, Bunce CM, Drayson MT. Murray JA, et al. Among authors: hayden re. Br J Haematol. 2010 Apr;149(1):65-9. doi: 10.1111/j.1365-2141.2009.08055.x. Epub 2010 Jan 13. Br J Haematol. 2010. PMID: 20067564 Free article. Clinical Trial.

4

The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.

Birtwistle J, Hayden RE, Khanim FL, Green RM, Pearce C, Davies NJ, Wake N, Schrewe H, Ride JP, Chipman JK, Bunce CM. Birtwistle J, et al. Among authors: hayden re. Mutat Res. 2009 Mar 9;662(1-2):67-74. doi: 10.1016/j.mrfmmm.2008.12.010. Epub 2008 Dec 31. Mutat Res. 2009. PMID: 19162045

5

Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone.

Lilly AJ, Khanim FL, Hayden RE, Luong QT, Drayson MT, Bunce CM. Lilly AJ, et al. Among authors: hayden re. Cancer Res. 2011 Feb 1;71(3):1177-86. doi: 10.1158/0008-5472.CAN-10-1704. Epub 2010 Dec 17. Cancer Res. 2011. PMID: 21169412

6

Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy.

Pearce C, Hayden RE, Bunce CM, Khanim FL. Pearce C, et al. Among authors: hayden re. BMC Cell Biol. 2009 Apr 28;10:31. doi: 10.1186/1471-2121-10-31. BMC Cell Biol. 2009. PMID: 19400951 Free PMC article.

7

Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia.

Khanim FL, Hayden RE, Birtwistle J, Lodi A, Tiziani S, Davies NJ, Ride JP, Viant MR, Gunther UL, Mountford JC, Schrewe H, Green RM, Murray JA, Drayson MT, Bunce CM. Khanim FL, et al. Among authors: hayden re. PLoS One. 2009 Dec 7;4(12):e8147. doi: 10.1371/journal.pone.0008147. PLoS One. 2009. PMID: 19997560 Free PMC article.

8

Lycorine sensitizes CD40 ligand-protected chronic lymphocytic leukemia cells to bezafibrate- and medroxyprogesterone acetate-induced apoptosis but dasatanib does not overcome reported CD40-mediated drug resistance.

Hayden RE, Pratt G, Drayson MT, Bunce CM. Hayden RE, et al. Haematologica. 2010 Nov;95(11):1889-96. doi: 10.3324/haematol.2010.027821. Epub 2010 Jul 15. Haematologica. 2010. PMID: 20634492 Free PMC article.

9

Treatment of chronic lymphocytic leukemia requires targeting of the protective lymph node environment with novel therapeutic approaches.

Hayden RE, Pratt G, Roberts C, Drayson MT, Bunce CM. Hayden RE, et al. Leuk Lymphoma. 2012 Apr;53(4):537-49. doi: 10.3109/10428194.2011.610014. Epub 2011 Sep 23. Leuk Lymphoma. 2012. PMID: 21812539 Review.

10

Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids.

Southam AD, Khanim FL, Hayden RE, Constantinou JK, Koczula KM, Michell RH, Viant MR, Drayson MT, Bunce CM. Southam AD, et al. Among authors: hayden re. Cancer Res. 2015 Jun 15;75(12):2530-40. doi: 10.1158/0008-5472.CAN-15-0202. Epub 2015 May 5. Cancer Res. 2015. PMID: 25943877

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