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Molecular basis of Pirh2-mediated p53 ubiquitylation.
Sheng Y, Laister RC, Lemak A, Wu B, Tai E, Duan S, Lukin J, Sunnerhagen M, Srisailam S, Karra M, Benchimol S, Arrowsmith CH. Sheng Y, et al. Among authors: benchimol s. Nat Struct Mol Biol. 2008 Dec;15(12):1334-42. doi: 10.1038/nsmb.1521. Epub 2008 Nov 30. Nat Struct Mol Biol. 2008. PMID: 19043414 Free PMC article.
TRIMming p53 for ubiquitination.
Tai E, Benchimol S. Tai E, et al. Among authors: benchimol s. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11431-2. doi: 10.1073/pnas.0905997106. Epub 2009 Jul 7. Proc Natl Acad Sci U S A. 2009. PMID: 19584248 Free PMC article. No abstract available.
Role of Pirh2 in mediating the regulation of p53 and c-Myc.
Hakem A, Bohgaki M, Lemmers B, Tai E, Salmena L, Matysiak-Zablocki E, Jung YS, Karaskova J, Kaustov L, Duan S, Madore J, Boutros P, Sheng Y, Chesi M, Bergsagel PL, Perez-Ordonez B, Mes-Masson AM, Penn L, Squire J, Chen X, Jurisica I, Arrowsmith C, Sanchez O, Benchimol S, Hakem R. Hakem A, et al. Among authors: benchimol s. PLoS Genet. 2011 Nov;7(11):e1002360. doi: 10.1371/journal.pgen.1002360. Epub 2011 Nov 17. PLoS Genet. 2011. PMID: 22125490 Free PMC article.
Structure and functionality of a designed p53 dimer.
Davison TS, Nie X, Ma W, Lin Y, Kay C, Benchimol S, Arrowsmith CH. Davison TS, et al. Among authors: benchimol s. J Mol Biol. 2001 Mar 23;307(2):605-17. doi: 10.1006/jmbi.2001.4450. J Mol Biol. 2001. PMID: 11254385
Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein.
Bagashev A, Fan S, Mukerjee R, Claudio PP, Chabrashvili T, Leng RP, Benchimol S, Sawaya BE. Bagashev A, et al. Among authors: benchimol s. Cell Cycle. 2013 May 15;12(10):1569-77. doi: 10.4161/cc.24733. Epub 2013 Apr 19. Cell Cycle. 2013. PMID: 23603988 Free PMC article.
118 results