Steegborn C - Search Results

1

Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans.

Schlicker C, Hall RA, Vullo D, Middelhaufe S, Gertz M, Supuran CT, Mühlschlegel FA, Steegborn C. Schlicker C, et al. Among authors: steegborn c. J Mol Biol. 2009 Jan 30;385(4):1207-20. doi: 10.1016/j.jmb.2008.11.037. Epub 2008 Nov 27. J Mol Biol. 2009. PMID: 19071134

2

Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.

Steegborn C, Laber B, Messerschmidt A, Huber R, Clausen T. Steegborn C, et al. J Mol Biol. 2001 Aug 24;311(4):789-801. doi: 10.1006/jmbi.2001.4880. J Mol Biol. 2001. PMID: 11518531

3

Crystal structure of the human CCA-adding enzyme: insights into template-independent polymerization.

Augustin MA, Reichert AS, Betat H, Huber R, Mörl M, Steegborn C. Augustin MA, et al. Among authors: steegborn c. J Mol Biol. 2003 May 16;328(5):985-94. doi: 10.1016/s0022-2836(03)00381-4. J Mol Biol. 2003. PMID: 12729736

4

Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1.

Mogensen EG, Janbon G, Chaloupka J, Steegborn C, Fu MS, Moyrand F, Klengel T, Pearson DS, Geeves MA, Buck J, Levin LR, Mühlschlegel FA. Mogensen EG, et al. Among authors: steegborn c. Eukaryot Cell. 2006 Jan;5(1):103-11. doi: 10.1128/EC.5.1.103-111.2006. Eukaryot Cell. 2006. PMID: 16400172 Free PMC article.

5

Molecular details of cAMP generation in mammalian cells: a tale of two systems.

Kamenetsky M, Middelhaufe S, Bank EM, Levin LR, Buck J, Steegborn C. Kamenetsky M, et al. Among authors: steegborn c. J Mol Biol. 2006 Sep 29;362(4):623-39. doi: 10.1016/j.jmb.2006.07.045. Epub 2006 Jul 28. J Mol Biol. 2006. PMID: 16934836 Free PMC article. Review.

6

Mapping the ADF/cofilin binding site on monomeric actin by competitive cross-linking and peptide array: evidence for a second binding site on monomeric actin.

Mannherz HG, Ballweber E, Galla M, Villard S, Granier C, Steegborn C, Schmidtmann A, Jaquet K, Pope B, Weeds AG. Mannherz HG, et al. Among authors: steegborn c. J Mol Biol. 2007 Feb 23;366(3):745-55. doi: 10.1016/j.jmb.2006.11.100. Epub 2006 Dec 15. J Mol Biol. 2007. PMID: 17196218

7

Domain mapping on the human metastasis regulator protein h-Prune reveals a C-terminal dimerization domain.

Middelhaufe S, Garzia L, Ohndorf UM, Kachholz B, Zollo M, Steegborn C. Middelhaufe S, et al. Among authors: steegborn c. Biochem J. 2007 Oct 15;407(2):199-205. doi: 10.1042/BJ20070408. Biochem J. 2007. PMID: 17655525 Free PMC article.

8

Activation of the lifespan regulator p66Shc through reversible disulfide bond formation.

Gertz M, Fischer F, Wolters D, Steegborn C. Gertz M, et al. Among authors: steegborn c. Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5705-9. doi: 10.1073/pnas.0800691105. Epub 2008 Apr 14. Proc Natl Acad Sci U S A. 2008. PMID: 18413607 Free PMC article.

9

Structure-based development of novel adenylyl cyclase inhibitors.

Schlicker C, Rauch A, Hess KC, Kachholz B, Levin LR, Buck J, Steegborn C. Schlicker C, et al. Among authors: steegborn c. J Med Chem. 2008 Aug 14;51(15):4456-64. doi: 10.1021/jm800481q. Epub 2008 Jul 17. J Med Chem. 2008. PMID: 18630896 Free PMC article.

10

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.

Schlicker C, Gertz M, Papatheodorou P, Kachholz B, Becker CF, Steegborn C. Schlicker C, et al. Among authors: steegborn c. J Mol Biol. 2008 Oct 10;382(3):790-801. doi: 10.1016/j.jmb.2008.07.048. Epub 2008 Jul 25. J Mol Biol. 2008. PMID: 18680753

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