Ha SJ - Search Results

1

IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection.

Brooks DG, Ha SJ, Elsaesser H, Sharpe AH, Freeman GJ, Oldstone MB. Brooks DG, et al. Among authors: ha sj. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20428-33. doi: 10.1073/pnas.0811139106. Epub 2008 Dec 15. Proc Natl Acad Sci U S A. 2008. PMID: 19075244 Free PMC article.

2

Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection.

Ha SJ, Mueller SN, Wherry EJ, Barber DL, Aubert RD, Sharpe AH, Freeman GJ, Ahmed R. Ha SJ, et al. J Exp Med. 2008 Mar 17;205(3):543-55. doi: 10.1084/jem.20071949. Epub 2008 Mar 10. J Exp Med. 2008. PMID: 18332181 Free PMC article.

3

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.

Mueller SN, Vanguri VK, Ha SJ, West EE, Keir ME, Glickman JN, Sharpe AH, Ahmed R. Mueller SN, et al. Among authors: ha sj. J Clin Invest. 2010 Jul;120(7):2508-15. doi: 10.1172/JCI40040. Epub 2010 Jun 14. J Clin Invest. 2010. PMID: 20551512 Free PMC article.

4

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

Jin HT, Anderson AC, Tan WG, West EE, Ha SJ, Araki K, Freeman GJ, Kuchroo VK, Ahmed R. Jin HT, et al. Among authors: ha sj. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14733-8. doi: 10.1073/pnas.1009731107. Epub 2010 Aug 2. Proc Natl Acad Sci U S A. 2010. PMID: 20679213 Free PMC article.

5

4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection.

Vezys V, Penaloza-MacMaster P, Barber DL, Ha SJ, Konieczny B, Freeman GJ, Mittler RS, Ahmed R. Vezys V, et al. Among authors: ha sj. J Immunol. 2011 Aug 15;187(4):1634-42. doi: 10.4049/jimmunol.1100077. Epub 2011 Jul 8. J Immunol. 2011. PMID: 21742975 Free PMC article.

6

Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection.

Aubert RD, Kamphorst AO, Sarkar S, Vezys V, Ha SJ, Barber DL, Ye L, Sharpe AH, Freeman GJ, Ahmed R. Aubert RD, et al. Among authors: ha sj. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21182-7. doi: 10.1073/pnas.1118450109. Epub 2011 Dec 12. Proc Natl Acad Sci U S A. 2011. PMID: 22160724 Free PMC article.

7

PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells.

West EE, Jin HT, Rasheed AU, Penaloza-Macmaster P, Ha SJ, Tan WG, Youngblood B, Freeman GJ, Smith KA, Ahmed R. West EE, et al. Among authors: ha sj. J Clin Invest. 2013 Jun;123(6):2604-15. doi: 10.1172/JCI67008. Epub 2013 May 15. J Clin Invest. 2013. PMID: 23676462 Free PMC article.

8

Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections.

Ha SJ, West EE, Araki K, Smith KA, Ahmed R. Ha SJ, et al. Immunol Rev. 2008 Jun;223:317-33. doi: 10.1111/j.1600-065X.2008.00638.x. Immunol Rev. 2008. PMID: 18613845 Review.

9

Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection.

Blattman JN, Wherry EJ, Ha SJ, van der Most RG, Ahmed R. Blattman JN, et al. Among authors: ha sj. J Virol. 2009 May;83(9):4386-94. doi: 10.1128/JVI.02524-08. Epub 2009 Feb 11. J Virol. 2009. PMID: 19211743 Free PMC article.

10

PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells.

Park HJ, Park JS, Jeong YH, Son J, Ban YH, Lee BH, Chen L, Chang J, Chung DH, Choi I, Ha SJ. Park HJ, et al. Among authors: ha sj. J Immunol. 2015 Jun 15;194(12):5801-11. doi: 10.4049/jimmunol.1401936. Epub 2015 May 1. J Immunol. 2015. PMID: 25934860

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