Verkaik NS - Search Results

1

A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.

van der Burg M, Ijspeert H, Verkaik NS, Turul T, Wiegant WW, Morotomi-Yano K, Mari PO, Tezcan I, Chen DJ, Zdzienicka MZ, van Dongen JJ, van Gent DC. van der Burg M, et al. Among authors: verkaik ns. J Clin Invest. 2009 Jan;119(1):91-8. doi: 10.1172/JCI37141. Epub 2008 Dec 15. J Clin Invest. 2009. PMID: 19075392 Free PMC article.

2

N-terminal truncated human RAG1 proteins can direct T-cell receptor but not immunoglobulin gene rearrangements.

Noordzij JG, Verkaik NS, Hartwig NG, de Groot R, van Gent DC, van Dongen JJ. Noordzij JG, et al. Among authors: verkaik ns. Blood. 2000 Jul 1;96(1):203-9. Blood. 2000. PMID: 10891452 Free article.

3

Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells.

Verkaik NS, Esveldt-van Lange RE, van Heemst D, Brüggenwirth HT, Hoeijmakers JH, Zdzienicka MZ, van Gent DC. Verkaik NS, et al. Eur J Immunol. 2002 Mar;32(3):701-9. doi: 10.1002/1521-4141(200203)32:3<701::AID-IMMU701>3.0.CO;2-T. Eur J Immunol. 2002. PMID: 11870614 Free article.

4

The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins.

Noordzij JG, de Bruin-Versteeg S, Verkaik NS, Vossen JM, de Groot R, Bernatowska E, Langerak AW, van Gent DC, van Dongen JJ. Noordzij JG, et al. Among authors: verkaik ns. Blood. 2002 Sep 15;100(6):2145-52. Blood. 2002. PMID: 12200379 Free article.

5

Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.

Noordzij JG, Verkaik NS, van der Burg M, van Veelen LR, de Bruin-Versteeg S, Wiegant W, Vossen JM, Weemaes CM, de Groot R, Zdzienicka MZ, van Gent DC, van Dongen JJ. Noordzij JG, et al. Among authors: verkaik ns. Blood. 2003 Feb 15;101(4):1446-52. doi: 10.1182/blood-2002-01-0187. Epub 2002 Oct 24. Blood. 2003. PMID: 12406895 Free article.

6

Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells.

Tauchi H, Kobayashi J, Morishima K, van Gent DC, Shiraishi T, Verkaik NS, vanHeems D, Ito E, Nakamura A, Sonoda E, Takata M, Takeda S, Matsuura S, Komatsu K. Tauchi H, et al. Among authors: verkaik ns. Nature. 2002 Nov 7;420(6911):93-8. doi: 10.1038/nature01125. Nature. 2002. PMID: 12422221

7

Multiple roles of Rev3, the catalytic subunit of polzeta in maintaining genome stability in vertebrates.

Sonoda E, Okada T, Zhao GY, Tateishi S, Araki K, Yamaizumi M, Yagi T, Verkaik NS, van Gent DC, Takata M, Takeda S. Sonoda E, et al. Among authors: verkaik ns. EMBO J. 2003 Jun 16;22(12):3188-97. doi: 10.1093/emboj/cdg308. EMBO J. 2003. PMID: 12805232 Free PMC article.

8

The role of DNA dependent protein kinase in synapsis of DNA ends.

Weterings E, Verkaik NS, Brüggenwirth HT, Hoeijmakers JH, van Gent DC. Weterings E, et al. Among authors: verkaik ns. Nucleic Acids Res. 2003 Dec 15;31(24):7238-46. doi: 10.1093/nar/gkg889. Nucleic Acids Res. 2003. PMID: 14654699 Free PMC article.

9

End-joining of blunt DNA double-strand breaks in mammalian fibroblasts is precise and requires DNA-PK and XRCC4.

van Heemst D, Brugmans L, Verkaik NS, van Gent DC. van Heemst D, et al. Among authors: verkaik ns. DNA Repair (Amst). 2004 Jan 5;3(1):43-50. doi: 10.1016/j.dnarep.2003.09.004. DNA Repair (Amst). 2004. PMID: 14697758

10

A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation.

van der Burg M, van Veelen LR, Verkaik NS, Wiegant WW, Hartwig NG, Barendregt BH, Brugmans L, Raams A, Jaspers NG, Zdzienicka MZ, van Dongen JJ, van Gent DC. van der Burg M, et al. Among authors: verkaik ns. J Clin Invest. 2006 Jan;116(1):137-45. doi: 10.1172/JCI26121. Epub 2005 Dec 15. J Clin Invest. 2006. PMID: 16357942 Free PMC article.

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