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Development of an UPLC-MS/MS method for quantification of Avitinib (AC0010) and its five metabolites in human cerebrospinal fluid: Application to a study of the blood-brain barrier penetration rate of non-small cell lung cancer patients.
Wang W, Zheng X, Wang H, Wang L, Jiang J, Hu P. Wang W, et al. Among authors: wang h, wang l. J Pharm Biomed Anal. 2017 May 30;139:205-214. doi: 10.1016/j.jpba.2017.02.057. Epub 2017 Mar 4. J Pharm Biomed Anal. 2017. PMID: 28285073
First-in-Human Phase I Study of AC0010, a Mutant-Selective EGFR Inhibitor in Non-Small Cell Lung Cancer: Safety, Efficacy, and Potential Mechanism of Resistance.
Ma Y, Zheng X, Zhao H, Fang W, Zhang Y, Ge J, Wang L, Wang W, Jiang J, Chuai S, Zhang Z, Xu W, Xu X, Hu P, Zhang L. Ma Y, et al. Among authors: wang w, wang l. J Thorac Oncol. 2018 Jul;13(7):968-977. doi: 10.1016/j.jtho.2018.03.025. Epub 2018 Apr 4. J Thorac Oncol. 2018. PMID: 29626621 Free article. Clinical Trial.
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