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The coincidence of chromosome 15 aberrations and beta2-microglobulin gene mutations is causative for the total loss of human leukocyte antigen class I expression in melanoma.
Paschen A, Arens N, Sucker A, Greulich-Bode KM, Fonsatti E, Gloghini A, Striegel S, Schwinn N, Carbone A, Hildenbrand R, Cerwenka A, Maio M, Schadendorf D. Paschen A, et al. Among authors: schwinn n. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3297-305. doi: 10.1158/1078-0432.CCR-05-2174. Clin Cancer Res. 2006. PMID: 16740750