O'Hayre M - Search Results

1

Modulation of chemokine receptor activity through dimerization and crosstalk.

Salanga CL, O'Hayre M, Handel T. Salanga CL, et al. Cell Mol Life Sci. 2009 Apr;66(8):1370-86. doi: 10.1007/s00018-008-8666-1. Cell Mol Life Sci. 2009. PMID: 19099182 Free PMC article. Review.

2

Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment.

O'Hayre M, Salanga CL, Handel TM, Allen SJ. O'Hayre M, et al. Biochem J. 2008 Feb 1;409(3):635-49. doi: 10.1042/BJ20071493. Biochem J. 2008. PMID: 18177271 Review.

3

Phosphoproteomic analysis of chemokine signaling networks.

O'Hayre M, Salanga CL, Dorrestein PC, Handel TM. O'Hayre M, et al. Methods Enzymol. 2009;460:331-46. doi: 10.1016/S0076-6879(09)05216-1. Methods Enzymol. 2009. PMID: 19446733

4

Elucidating the CXCL12/CXCR4 signaling network in chronic lymphocytic leukemia through phosphoproteomics analysis.

O'Hayre M, Salanga CL, Kipps TJ, Messmer D, Dorrestein PC, Handel TM. O'Hayre M, et al. PLoS One. 2010 Jul 22;5(7):e11716. doi: 10.1371/journal.pone.0011716. PLoS One. 2010. PMID: 20661426 Free PMC article.

5

Emerging concepts and approaches for chemokine-receptor drug discovery.

O'Hayre M, Salanga CL, Handel TM, Hamel DJ. O'Hayre M, et al. Expert Opin Drug Discov. 2010 Nov;5(11):1109-22. doi: 10.1517/17460441.2010.525633. Expert Opin Drug Discov. 2010. PMID: 21132095 Free PMC article. Review.

6

Chronic lymphocytic leukemia cells receive RAF-dependent survival signals in response to CXCL12 that are sensitive to inhibition by sorafenib.

Messmer D, Fecteau JF, O'Hayre M, Bharati IS, Handel TM, Kipps TJ. Messmer D, et al. Blood. 2011 Jan 20;117(3):882-9. doi: 10.1182/blood-2010-04-282400. Epub 2010 Nov 15. Blood. 2011. PMID: 21079155 Free PMC article.

7

Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1).

Fecteau JF, Bharati IS, O'Hayre M, Handel TM, Kipps TJ, Messmer D. Fecteau JF, et al. Mol Med. 2012 Feb 10;18(1):19-28. doi: 10.2119/molmed.2011.00164. Mol Med. 2012. PMID: 21979753 Free PMC article.

8

The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer.

O'Hayre M, Vázquez-Prado J, Kufareva I, Stawiski EW, Handel TM, Seshagiri S, Gutkind JS. O'Hayre M, et al. Nat Rev Cancer. 2013 Jun;13(6):412-24. doi: 10.1038/nrc3521. Epub 2013 May 3. Nat Rev Cancer. 2013. PMID: 23640210 Free PMC article. Review.

9

Mechanisms and consequences of the loss of PHLPP1 phosphatase in chronic lymphocytic leukemia (CLL).

O'Hayre M, Niederst M, Fecteau JF, Nguyen VM, Kipps TJ, Messmer D, Newton AC, Handel TM. O'Hayre M, et al. Leukemia. 2012 Jul;26(7):1689-92. doi: 10.1038/leu.2012.6. Epub 2012 Jan 12. Leukemia. 2012. PMID: 22237780 Free PMC article. No abstract available.

10

Genetic evidence that β-arrestins are dispensable for the initiation of β₂-adrenergic receptor signaling to ERK.

O'Hayre M, Eichel K, Avino S, Zhao X, Steffen DJ, Feng X, Kawakami K, Aoki J, Messer K, Sunahara R, Inoue A, von Zastrow M, Gutkind JS. O'Hayre M, et al. Sci Signal. 2017 Jun 20;10(484):eaal3395. doi: 10.1126/scisignal.aal3395. Sci Signal. 2017. PMID: 28634209 Free PMC article.

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