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Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.
Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, Biswal S. Sussan TE, et al. Among authors: tuder rm. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):250-5. doi: 10.1073/pnas.0804333106. Epub 2008 Dec 22. Proc Natl Acad Sci U S A. 2009. PMID: 19104057 Free PMC article.
Regression of chronic hypoxic pulmonary hypertension by simvastatin.
Girgis RE, Mozammel S, Champion HC, Li D, Peng X, Shimoda L, Tuder RM, Johns RA, Hassoun PM. Girgis RE, et al. Among authors: tuder rm. Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1105-10. doi: 10.1152/ajplung.00411.2006. Epub 2007 Feb 2. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17277047 Free article.
Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice.
Papaiahgari S, Yerrapureddy A, Reddy SR, Reddy NM, Dodd-O JM, Crow MT, Grigoryev DN, Barnes K, Tuder RM, Yamamoto M, Kensler TW, Biswal S, Mitzner W, Hassoun PM, Reddy SP. Papaiahgari S, et al. Among authors: tuder rm. Am J Respir Crit Care Med. 2007 Dec 15;176(12):1222-35. doi: 10.1164/rccm.200701-060OC. Epub 2007 Sep 27. Am J Respir Crit Care Med. 2007. PMID: 17901416 Free PMC article.
346 results