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Page 1
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Among authors: meikle pj. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease.
Baloni P, Funk CC, Yan J, Yurkovich JT, Kueider-Paisley A, Nho K, Heinken A, Jia W, Mahmoudiandehkordi S, Louie G, Saykin AJ, Arnold M, Kastenmüller G, Griffiths WJ, Thiele I; Alzheimer’s Disease Metabolomics Consortium; Kaddurah-Daouk R, Price ND. Baloni P, et al. Cell Rep Med. 2020 Nov 17;1(8):100138. doi: 10.1016/j.xcrm.2020.100138. eCollection 2020 Nov 17. Cell Rep Med. 2020. PMID: 33294859 Free PMC article.
Reduced PI3K(p110α) induces atrial myopathy, and PI3K-related lipids are dysregulated in athletes with atrial fibrillation.
Bass-Stringer S, Bernardo BC, Yildiz GS, Matsumoto A, Kiriazis H, Harmawan CA, Tai CMK, Chooi R, Bottrell L, Ezeani M, Donner DG, D'Elia AA, Ooi JYY, Mellett NA, Luo J, Masterman EI, Janssens K, Olshansky G, Howden EJ, Cross JH, Hagemeyer CE, Lin RCY, Thomas CJ, Magor GW, Perkins AC, Marwick TH, Kawakami H, Meikle PJ, Greening DW, Weeks KL, La Gerche A, Tham YK, McMullen JR. Bass-Stringer S, et al. Among authors: meikle pj. J Sport Health Sci. 2025 Jan 16:101023. doi: 10.1016/j.jshs.2025.101023. Online ahead of print. J Sport Health Sci. 2025. PMID: 39826614 Free article.
An optimized plasmalogen modulating dietary supplement provides greater protection in a male than female mouse model of dilated cardiomyopathy.
Belkin TG, Masterman EI, Yildiz GS, Kiriazis H, Mellett NA, Cross J, Grigolon K, Dogra A, Donner D, Chooi R, Liang A, Kompa AR, Sadoshima J, Edgley AJ, Greening DW, Meikle PJ, Tham YK, McMullen JR. Belkin TG, et al. Among authors: meikle pj. J Mol Cell Cardiol Plus. 2024 Dec 4;11:100273. doi: 10.1016/j.jmccpl.2024.100273. eCollection 2025 Mar. J Mol Cell Cardiol Plus. 2024. PMID: 39802264 Free PMC article.
Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer's disease in humans.
Neth BJ, Huynh K, Giles C, Wang T, Mellett NA, Duong T, Blach C, Schimmel L, Register TC, Blennow K, Zetterberg H, Batra R, Schweickart A, Dilmore AH, Martino C, Arnold M, Krumsiek J, Han X, Dorrestein PC, Knight R, Meikle PJ, Craft S, Kaddurah-Daouk R. Neth BJ, et al. Among authors: meikle pj. Commun Med (Lond). 2025 Jan 9;5(1):11. doi: 10.1038/s43856-024-00682-w. Commun Med (Lond). 2025. PMID: 39779882 Free PMC article.
Evolocumab in metastatic castration-resistant prostate cancer: study protocol for a single-arm, phase II trial, and initial experience with use of a validated lipid biomarker to direct therapy.
Mellor R, Ardolino L, Scheinberg T, Fitzpatrick M, Lin HM, Bonnitcha P, Sullivan D, Meikle PJ, Stockler MR, Moujaber T, Joshua A, Horvath L. Mellor R, et al. Among authors: meikle pj. Ther Adv Med Oncol. 2024 Dec 16;16:17588359241307814. doi: 10.1177/17588359241307814. eCollection 2024. Ther Adv Med Oncol. 2024. PMID: 39691585 Free PMC article.
Personalized Profiling of Lipoprotein and Lipid Metabolism Based on 1018 Measures from Combined Quantitative NMR and LC-MS/MS Platforms.
Zhao S, Giles C, Huynh K, Kettunen J, Järvelin MR, Kähönen M, Viikari J, Lehtimäki T, Raitakari OT, Meikle PJ, Mäkinen VP, Ala-Korpela M. Zhao S, et al. Among authors: meikle pj. Anal Chem. 2024 Dec 16;96(52):20362-70. doi: 10.1021/acs.analchem.4c03229. Online ahead of print. Anal Chem. 2024. PMID: 39680883 Free PMC article.
329 results