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Discovery of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride: a novel, potent and orally active direct inhibitor of factor Xa.
Nagata T, Yoshino T, Haginoya N, Yoshikawa K, Nagamochi M, Kobayashi S, Komoriya S, Yokomizo A, Muto R, Yamaguchi M, Osanai K, Suzuki M, Kanno H. Nagata T, et al. Among authors: yamaguchi m. Bioorg Med Chem. 2009 Feb 1;17(3):1193-206. doi: 10.1016/j.bmc.2008.12.037. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19128974
Discovery of novel pyrrole derivatives as potent agonists for the niacin receptor GPR109A.
Miyazawa Y, Yamaguchi T, Yamaguchi M, Tago K, Tamura A, Sugiyama D, Aburatani T, Nishizawa T, Kurikawa N, Kono K. Miyazawa Y, et al. Among authors: yamaguchi t, yamaguchi m. Bioorg Med Chem Lett. 2020 May 15;30(10):127105. doi: 10.1016/j.bmcl.2020.127105. Epub 2020 Mar 10. Bioorg Med Chem Lett. 2020. PMID: 32199732 Free article.
Synthesis and structure-activity relationships of novel zwitterionic compounds as peroxisome proliferator activated receptor α/γ dual agonists with improved physicochemical properties.
Shibata Y, Kagechika K, Yamaguchi M, Yoshikawa K, Chiba K, Takano H, Akiyama C, Ono M, Nishi M, Kubo H, Kobayashi Y, Usui H. Shibata Y, et al. Among authors: yamaguchi m. Chem Pharm Bull (Tokyo). 2013;61(12):1248-63. doi: 10.1248/cpb.c13-00513. Chem Pharm Bull (Tokyo). 2013. PMID: 24292787 Free article.
6,067 results