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A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge.
Zhang X, Chentoufi AA, Dasgupta G, Nesburn AB, Wu M, Zhu X, Carpenter D, Wechsler SL, You S, BenMohamed L. Zhang X, et al. Among authors: wechsler sl. Mucosal Immunol. 2009 Mar;2(2):129-143. doi: 10.1038/mi.2008.81. Epub 2008 Dec 24. Mucosal Immunol. 2009. PMID: 19129756 Free PMC article.
Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.
Nesburn AB, Bettahi I, Dasgupta G, Chentoufi AA, Zhang X, You S, Morishige N, Wahlert AJ, Brown DJ, Jester JV, Wechsler SL, BenMohamed L. Nesburn AB, et al. Among authors: wechsler sl. J Virol. 2007 Jul;81(14):7647-61. doi: 10.1128/JVI.00294-07. Epub 2007 May 2. J Virol. 2007. PMID: 17475646 Free PMC article.
Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization.
Chentoufi AA, Dasgupta G, Nesburn AB, Bettahi I, Binder NR, Choudhury ZS, Chamberlain WD, Wechsler SL, BenMohamed L. Chentoufi AA, et al. Among authors: wechsler sl. Clin Vaccine Immunol. 2010 Mar;17(3):342-53. doi: 10.1128/CVI.00347-09. Epub 2010 Jan 20. Clin Vaccine Immunol. 2010. PMID: 20089796 Free PMC article.
The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism.
Chentoufi AA, Kritzer E, Tran MV, Dasgupta G, Lim CH, Yu DC, Afifi RE, Jiang X, Carpenter D, Osorio N, Hsiang C, Nesburn AB, Wechsler SL, BenMohamed L. Chentoufi AA, et al. Among authors: wechsler sl. J Virol. 2011 Sep;85(17):9127-38. doi: 10.1128/JVI.00587-11. Epub 2011 Jun 29. J Virol. 2011. PMID: 21715478 Free PMC article.
154 results