Khanim FL - Search Results

1

Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines.

Tiziani S, Lodi A, Khanim FL, Viant MR, Bunce CM, Günther UL. Tiziani S, et al. Among authors: khanim fl. PLoS One. 2009;4(1):e4251. doi: 10.1371/journal.pone.0004251. Epub 2009 Jan 22. PLoS One. 2009. PMID: 19158949 Free PMC article.

2

PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC.

Hampson P, Chahal H, Khanim F, Hayden R, Mulder A, Assi LK, Bunce CM, Lord JM. Hampson P, et al. Blood. 2005 Aug 15;106(4):1362-8. doi: 10.1182/blood-2004-10-4117. Epub 2005 Apr 21. Blood. 2005. PMID: 15845901 Free article.

3

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

Bradbury CA, Khanim FL, Hayden R, Bunce CM, White DA, Drayson MT, Craddock C, Turner BM. Bradbury CA, et al. Among authors: khanim fl. Leukemia. 2005 Oct;19(10):1751-9. doi: 10.1038/sj.leu.2403910. Leukemia. 2005. PMID: 16121216

4

Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2.

Hayden RE, Pratt G, Davies NJ, Khanim FL, Birtwistle J, Delgado J, Pearce C, Sant T, Drayson MT, Bunce CM. Hayden RE, et al. Among authors: khanim fl. Leukemia. 2009 Feb;23(2):292-304. doi: 10.1038/leu.2008.283. Epub 2008 Oct 16. Leukemia. 2009. PMID: 18923439

5

Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy.

Pearce C, Hayden RE, Bunce CM, Khanim FL. Pearce C, et al. Among authors: khanim fl. BMC Cell Biol. 2009 Apr 28;10:31. doi: 10.1186/1471-2121-10-31. BMC Cell Biol. 2009. PMID: 19400951 Free PMC article.

6

Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia.

Khanim FL, Hayden RE, Birtwistle J, Lodi A, Tiziani S, Davies NJ, Ride JP, Viant MR, Gunther UL, Mountford JC, Schrewe H, Green RM, Murray JA, Drayson MT, Bunce CM. Khanim FL, et al. PLoS One. 2009 Dec 7;4(12):e8147. doi: 10.1371/journal.pone.0008147. PLoS One. 2009. PMID: 19997560 Free PMC article.

7

Elevated NCOR1 disrupts PPARalpha/gamma signaling in prostate cancer and forms a targetable epigenetic lesion.

Battaglia S, Maguire O, Thorne JL, Hornung LB, Doig CL, Liu S, Sucheston LE, Bianchi A, Khanim FL, Gommersall LM, Coulter HS, Rakha S, Giddings I, O'Neill LP, Cooper CS, McCabe CJ, Bunce CM, Campbell MJ. Battaglia S, et al. Among authors: khanim fl. Carcinogenesis. 2010 Sep;31(9):1650-60. doi: 10.1093/carcin/bgq086. Epub 2010 May 13. Carcinogenesis. 2010. PMID: 20466759 Free PMC article.

8

Extracellular Nm23H1 stimulates neurite outgrowth from dorsal root ganglia neurons in vitro independently of nerve growth factor supplementation or its nucleoside diphosphate kinase activity.

Wright KT, Seabright R, Logan A, Lilly AJ, Khanim F, Bunce CM, Johnson WE. Wright KT, et al. Biochem Biophys Res Commun. 2010 Jul 16;398(1):79-85. doi: 10.1016/j.bbrc.2010.06.039. Epub 2010 Jun 15. Biochem Biophys Res Commun. 2010. PMID: 20558132 Free article.

9

Hypoxia triggers major metabolic changes in AML cells without altering indomethacin-induced TCA cycle deregulation.

Lodi A, Tiziani S, Khanim FL, Drayson MT, Günther UL, Bunce CM, Viant MR. Lodi A, et al. Among authors: khanim fl. ACS Chem Biol. 2011 Feb 18;6(2):169-75. doi: 10.1021/cb900300j. Epub 2010 Oct 18. ACS Chem Biol. 2011. PMID: 20886892 Free PMC article.

10

Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone.

Lilly AJ, Khanim FL, Hayden RE, Luong QT, Drayson MT, Bunce CM. Lilly AJ, et al. Among authors: khanim fl. Cancer Res. 2011 Feb 1;71(3):1177-86. doi: 10.1158/0008-5472.CAN-10-1704. Epub 2010 Dec 17. Cancer Res. 2011. PMID: 21169412

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