Laughton D - Search Results

1

Discovery of small molecule human C5a receptor antagonists.

Sanganee HJ, Baxter A, Barber S, Brown AJ, Grice D, Hunt F, King S, Laughton D, Pairaudeau G, Thong B, Weaver R, Unitt J. Sanganee HJ, et al. Among authors: laughton d. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1143-7. doi: 10.1016/j.bmcl.2008.12.104. Epub 2008 Dec 31. Bioorg Med Chem Lett. 2009. PMID: 19171482

2

Synthesis and biological evaluation of N-alkylated 8-oxybenz[c]azepine derivatives as selective PPARδ agonists.

Luckhurst CA, Ratcliffe M, Stein L, Furber M, Botterell S, Laughton D, Tomlinson W, Weaver R, Chohan K, Walding A. Luckhurst CA, et al. Among authors: laughton d. Bioorg Med Chem Lett. 2011 Jan 1;21(1):531-6. doi: 10.1016/j.bmcl.2010.10.083. Epub 2010 Oct 23. Bioorg Med Chem Lett. 2011. PMID: 21075629

3

Potent reversible inhibition of myeloperoxidase by aromatic hydroxamates.

Forbes LV, Sjögren T, Auchère F, Jenkins DW, Thong B, Laughton D, Hemsley P, Pairaudeau G, Turner R, Eriksson H, Unitt JF, Kettle AJ. Forbes LV, et al. Among authors: laughton d. J Biol Chem. 2013 Dec 20;288(51):36636-47. doi: 10.1074/jbc.M113.507756. Epub 2013 Nov 5. J Biol Chem. 2013. PMID: 24194519 Free PMC article.

4

Human peripheral blood mononuclear cells express GABAA receptor subunits.

Alam S, Laughton DL, Walding A, Wolstenholme AJ. Alam S, et al. Mol Immunol. 2006 Mar;43(9):1432-42. doi: 10.1016/j.molimm.2005.07.025. Epub 2005 Oct 4. Mol Immunol. 2006. PMID: 16213022

5

Cloning of a putative inhibitory amino acid receptor subunit from the parasitic nematode Haemonchus contortus.

Laughton DL, Amar M, Thomas P, Towner P, Harris P, Lunt GG, Wolstenholme AJ. Laughton DL, et al. Recept Channels. 1994;2(2):155-63. Recept Channels. 1994. PMID: 7525001

6

The beta-subunit of Caenorhabditis elegans avermectin receptor responds to glycine and is encoded by chromosome 1.

Laughton DL, Wheeler SV, Lunt GG, Wolstenholme AJ. Laughton DL, et al. J Neurochem. 1995 May;64(5):2354-7. doi: 10.1046/j.1471-4159.1995.64052354.x. J Neurochem. 1995. PMID: 7536811

7

Reporter gene constructs suggest that the Caenorhabditis elegans avermectin receptor beta-subunit is expressed solely in the pharynx.

Laughton DL, Lunt GG, Wolstenholme AJ. Laughton DL, et al. J Exp Biol. 1997 May;200(Pt 10):1509-14. doi: 10.1242/jeb.200.10.1509. J Exp Biol. 1997. PMID: 9192499

8

Alternative splicing of a Caenorhabditis elegans gene produces two novel inhibitory amino acid receptor subunits with identical ligand binding domains but different ion channels.

Laughton DL, Lunt GG, Wolstenholme AJ. Laughton DL, et al. Gene. 1997 Nov 12;201(1-2):119-25. doi: 10.1016/s0378-1119(97)00436-8. Gene. 1997. PMID: 9409779

9

Cloning and localisation of an avermectin receptor-related subunit from Haemonchus contortus.

Delany NS, Laughton DL, Wolstenholme AJ. Delany NS, et al. Among authors: laughton dl. Mol Biochem Parasitol. 1998 Nov 30;97(1-2):177-87. doi: 10.1016/s0166-6851(98)00148-0. Mol Biochem Parasitol. 1998. PMID: 9879896

10

Ligand-gated chloride channel subunits encoded by the Haemonchus contortus and Ascaris suum orthologues of the Caenorhabditis elegans gbr-2 (avr-14) gene.

Jagannathan S, Laughton DL, Critten CL, Skinner TM, Horoszok L, Wolstenholme AJ. Jagannathan S, et al. Among authors: laughton dl. Mol Biochem Parasitol. 1999 Oct 15;103(2):129-40. doi: 10.1016/s0166-6851(99)00120-6. Mol Biochem Parasitol. 1999. PMID: 10551358

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