Müller HH - Search Results

1

Flexible designs for genomewide association studies.

Scherag A, Hebebrand J, Schäfer H, Müller HH. Scherag A, et al. Among authors: muller hh. Biometrics. 2009 Sep;65(3):815-21. doi: 10.1111/j.1541-0420.2008.01174.x. Epub 2009 Jan 23. Biometrics. 2009. PMID: 19173695

2

Data adaptive interim modification of sample sizes for candidate-gene association studies.

Scherag A, Müller HH, Dempfle A, Hebebrand J, Schäfer H. Scherag A, et al. Among authors: muller hh. Hum Hered. 2003;56(1-3):56-62. doi: 10.1159/000073733. Hum Hered. 2003. PMID: 14614239

3

Including sampling and phenotyping costs into the optimization of two stage designs for genomewide association studies.

Müller HH, Pahl R, Schäfer H. Müller HH, et al. Genet Epidemiol. 2007 Dec;31(8):844-52. doi: 10.1002/gepi.20245. Genet Epidemiol. 2007. PMID: 17549751

4

Optimal multistage designs--a general framework for efficient genome-wide association studies.

Pahl R, Schäfer H, Müller HH. Pahl R, et al. Among authors: muller hh. Biostatistics. 2009 Apr;10(2):297-309. doi: 10.1093/biostatistics/kxn036. Epub 2008 Dec 15. Biostatistics. 2009. PMID: 19075295

5

Adaptive group sequential designs for clinical trials: combining the advantages of adaptive and of classical group sequential approaches.

Müller HH, Schäfer H. Müller HH, et al. Biometrics. 2001 Sep;57(3):886-91. doi: 10.1111/j.0006-341x.2001.00886.x. Biometrics. 2001. PMID: 11550941

6

Reducing sample sizes in genome scans: group sequential study designs with futility stops.

König IR, Schäfer H, Ziegler A, Müller HH. König IR, et al. Among authors: muller hh. Genet Epidemiol. 2003 Dec;25(4):339-49. doi: 10.1002/gepi.10265. Genet Epidemiol. 2003. PMID: 14639703

7

Construction of group sequential designs in clinical trials on the basis of detectable treatment differences.

Schäfer H, Müller HH. Schäfer H, et al. Among authors: muller hh. Stat Med. 2004 May 15;23(9):1413-24. doi: 10.1002/sim.1751. Stat Med. 2004. PMID: 15116350

8

A general statistical principle for changing a design any time during the course of a trial.

Müller HH, Schäfer H. Müller HH, et al. Stat Med. 2004 Aug 30;23(16):2497-508. doi: 10.1002/sim.1852. Stat Med. 2004. PMID: 15287080

9

An overview of statistical approaches for adaptive designs and design modifications.

Schäfer H, Timmesfeld N, Müller HH. Schäfer H, et al. Among authors: muller hh. Biom J. 2006 Aug;48(4):507-20. doi: 10.1002/bimj.200510234. Biom J. 2006. PMID: 16972702 Review.

10

Increasing the sample size during clinical trials with t-distributed test statistics without inflating the type I error rate.

Timmesfeld N, Schäfer H, Müller HH. Timmesfeld N, et al. Among authors: muller hh. Stat Med. 2007 May 30;26(12):2449-64. doi: 10.1002/sim.2725. Stat Med. 2007. PMID: 17080491

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