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The humanized CD40 antibody SGN-40 demonstrates pre-clinical activity that is enhanced by lenalidomide in chronic lymphocytic leukaemia.
Lapalombella R, Gowda A, Joshi T, Mehter N, Cheney C, Lehman A, Chen CS, Johnson AJ, Caligiuri MA, Tridandapani S, Muthusamy N, Byrd JC. Lapalombella R, et al. Among authors: joshi t. Br J Haematol. 2009 Mar;144(6):848-55. doi: 10.1111/j.1365-2141.2008.07548.x. Epub 2009 Jan 12. Br J Haematol. 2009. PMID: 19183192 Free PMC article.
FcgammaR-induced production of superoxide and inflammatory cytokines is differentially regulated by SHIP through its influence on PI3K and/or Ras/Erk pathways.
Ganesan LP, Joshi T, Fang H, Kutala VK, Roda J, Trotta R, Lehman A, Kuppusamy P, Byrd JC, Carson WE, Caligiuri MA, Tridandapani S. Ganesan LP, et al. Among authors: joshi t. Blood. 2006 Jul 15;108(2):718-25. doi: 10.1182/blood-2005-09-3889. Epub 2006 Mar 16. Blood. 2006. PMID: 16543474 Free PMC article.
Fcgamma receptor signaling in phagocytes.
Joshi T, Butchar JP, Tridandapani S. Joshi T, et al. Int J Hematol. 2006 Oct;84(3):210-6. doi: 10.1532/IJH97.06140. Int J Hematol. 2006. PMID: 17050193 Review.
Targeting CD37-positive lymphoid malignancies with a novel engineered small modular immunopharmaceutical.
Zhao X, Lapalombella R, Joshi T, Cheney C, Gowda A, Hayden-Ledbetter MS, Baum PR, Lin TS, Jarjoura D, Lehman A, Kussewitt D, Lee RJ, Caligiuri MA, Tridandapani S, Muthusamy N, Byrd JC. Zhao X, et al. Among authors: joshi t. Blood. 2007 Oct 1;110(7):2569-77. doi: 10.1182/blood-2006-12-062927. Epub 2007 Apr 17. Blood. 2007. PMID: 17440052 Free PMC article.
IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro.
Gowda A, Roda J, Hussain SR, Ramanunni A, Joshi T, Schmidt S, Zhang X, Lehman A, Jarjoura D, Carson WE, Kindsvogel W, Cheney C, Caligiuri MA, Tridandapani S, Muthusamy N, Byrd JC. Gowda A, et al. Among authors: joshi t. Blood. 2008 May 1;111(9):4723-30. doi: 10.1182/blood-2007-07-099531. Epub 2008 Jan 8. Blood. 2008. PMID: 18182577 Free PMC article.
Fcγ Receptor Signaling in Phagocytes.
Joshi T, Butchar JP, Tridandapani S. Joshi T, et al. Int J Hematol. 2006 Oct;84(3):210-216. doi: 10.1532/IJH97.06140. Epub 2018 Jan 16. Int J Hematol. 2006. PMID: 29349684
An association analysis between psychophysical characteristics and genome-wide gene expression changes in human adaptation to the extreme climate at the Antarctic Dome Argus.
Xu C, Ju X, Song D, Huang F, Tang D, Zou Z, Zhang C, Joshi T, Jia L, Xu W, Xu KF, Wang Q, Xiong Y, Guo Z, Chen X, Huang F, Xu J, Zhong Y, Zhu Y, Peng Y, Wang L, Zhang X, Jiang R, Li D, Jiang T, Xu D, Jiang C. Xu C, et al. Among authors: joshi t. Mol Psychiatry. 2015 Apr;20(4):536-44. doi: 10.1038/mp.2014.72. Epub 2014 Sep 9. Mol Psychiatry. 2015. PMID: 25199918 Free article.
577 results