Brodsky JL - Search Results

1

Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum.

Chiang AN, Valderramos JC, Balachandran R, Chovatiya RJ, Mead BP, Schneider C, Bell SL, Klein MG, Huryn DM, Chen XS, Day BW, Fidock DA, Wipf P, Brodsky JL. Chiang AN, et al. Among authors: brodsky jl. Bioorg Med Chem. 2009 Feb 15;17(4):1527-33. doi: 10.1016/j.bmc.2009.01.024. Epub 2009 Jan 20. Bioorg Med Chem. 2009. PMID: 19195901 Free PMC article.

2

Identification of an inhibitor of hsc70-mediated protein translocation and ATP hydrolysis.

Fewell SW, Day BW, Brodsky JL. Fewell SW, et al. Among authors: brodsky jl. J Biol Chem. 2001 Jan 12;276(2):910-4. doi: 10.1074/jbc.M008535200. J Biol Chem. 2001. PMID: 11036084 Free article.

3

Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity.

Fewell SW, Smith CM, Lyon MA, Dumitrescu TP, Wipf P, Day BW, Brodsky JL. Fewell SW, et al. Among authors: brodsky jl. J Biol Chem. 2004 Dec 3;279(49):51131-40. doi: 10.1074/jbc.M404857200. Epub 2004 Sep 23. J Biol Chem. 2004. PMID: 15448148 Free article.

4

Hsp70 molecular chaperones: emerging roles in human disease and identification of small molecule modulators.

Brodsky JL, Chiosis G. Brodsky JL, et al. Curr Top Med Chem. 2006;6(11):1215-25. doi: 10.2174/156802606777811997. Curr Top Med Chem. 2006. PMID: 16842158 Review.

5

The Hsp110 molecular chaperone stabilizes apolipoprotein B from endoplasmic reticulum-associated degradation (ERAD).

Hrizo SL, Gusarova V, Habiel DM, Goeckeler JL, Fisher EA, Brodsky JL. Hrizo SL, et al. Among authors: brodsky jl. J Biol Chem. 2007 Nov 9;282(45):32665-75. doi: 10.1074/jbc.M705216200. Epub 2007 Sep 6. J Biol Chem. 2007. PMID: 17823116 Free PMC article.

6

Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation.

Wright CM, Chovatiya RJ, Jameson NE, Turner DM, Zhu G, Werner S, Huryn DM, Pipas JM, Day BW, Wipf P, Brodsky JL. Wright CM, et al. Among authors: brodsky jl. Bioorg Med Chem. 2008 Mar 15;16(6):3291-301. doi: 10.1016/j.bmc.2007.12.014. Epub 2007 Dec 14. Bioorg Med Chem. 2008. PMID: 18164205 Free PMC article.

7

The yeast Hsp110, Sse1p, exhibits high-affinity peptide binding.

Goeckeler JL, Petruso AP, Aguirre J, Clement CC, Chiosis G, Brodsky JL. Goeckeler JL, et al. Among authors: brodsky jl. FEBS Lett. 2008 Jul 9;582(16):2393-6. doi: 10.1016/j.febslet.2008.05.047. Epub 2008 Jun 6. FEBS Lett. 2008. PMID: 18539149 Free PMC article.

8

A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum.

Rabu C, Wipf P, Brodsky JL, High S. Rabu C, et al. Among authors: brodsky jl. J Biol Chem. 2008 Oct 10;283(41):27504-27513. doi: 10.1074/jbc.M804591200. Epub 2008 Jul 29. J Biol Chem. 2008. PMID: 18667436 Free PMC article.

9

Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities.

Patham B, Duffy J, Lane A, Davis RC, Wipf P, Fewell SW, Brodsky JL, Mensa-Wilmot K. Patham B, et al. Among authors: brodsky jl. Biochem J. 2009 Apr 15;419(2):507-17. doi: 10.1042/BJ20081787. Biochem J. 2009. PMID: 19196237 Free PMC article.

10

Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen.

Wright CM, Seguin SP, Fewell SW, Zhang H, Ishwad C, Vats A, Lingwood CA, Wipf P, Fanning E, Pipas JM, Brodsky JL. Wright CM, et al. Among authors: brodsky jl. Virus Res. 2009 Apr;141(1):71-80. doi: 10.1016/j.virusres.2008.12.018. Epub 2009 Feb 4. Virus Res. 2009. PMID: 19200446 Free PMC article.

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