O'Connor SE - Search Results

1

Opportunities for enzyme engineering in natural product biosynthesis.

Bernhardt P, O'Connor SE. Bernhardt P, et al. Curr Opin Chem Biol. 2009 Feb;13(1):35-42. doi: 10.1016/j.cbpa.2009.01.005. Epub 2009 Feb 5. Curr Opin Chem Biol. 2009. PMID: 19201253 Free PMC article. Review.

2

Directed biosynthesis of alkaloid analogs in the medicinal plant Catharanthus roseus.

McCoy E, O'Connor SE. McCoy E, et al. J Am Chem Soc. 2006 Nov 8;128(44):14276-7. doi: 10.1021/ja066787w. J Am Chem Soc. 2006. PMID: 17076499

3

Redesign of a central enzyme in alkaloid biosynthesis.

Chen S, Galan MC, Coltharp C, O'Connor SE. Chen S, et al. Chem Biol. 2006 Nov;13(11):1137-41. doi: 10.1016/j.chembiol.2006.10.009. Chem Biol. 2006. PMID: 17113995

4

Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle.

Bernhardt P, McCoy E, O'Connor SE. Bernhardt P, et al. Chem Biol. 2007 Aug;14(8):888-97. doi: 10.1016/j.chembiol.2007.07.008. Chem Biol. 2007. PMID: 17719488 Free PMC article.

5

Natural products from plant cell cultures.

McCoy E, O'Connor SE. McCoy E, et al. Prog Drug Res. 2008;65:329, 331-70. Prog Drug Res. 2008. PMID: 18084920 Review.

6

Metabolic reprogramming of periwinkle plant culture.

Runguphan W, O'Connor SE. Runguphan W, et al. Nat Chem Biol. 2009 Mar;5(3):151-3. doi: 10.1038/nchembio.141. Epub 2009 Jan 18. Nat Chem Biol. 2009. PMID: 19151732 Free PMC article.

7

Mechanistic advances in plant natural product enzymes.

Usera AR, O'Connor SE. Usera AR, et al. Curr Opin Chem Biol. 2009 Oct;13(4):492-8. doi: 10.1016/j.cbpa.2009.06.019. Epub 2009 Jul 23. Curr Opin Chem Biol. 2009. PMID: 19632140 Free PMC article. Review.

8

Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture.

Runguphan W, Maresh JJ, O'Connor SE. Runguphan W, et al. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13673-8. doi: 10.1073/pnas.0903393106. Epub 2009 Aug 5. Proc Natl Acad Sci U S A. 2009. PMID: 19666570 Free PMC article.

9

Bypassing stereoselectivity in the early steps of alkaloid biosynthesis.

Bernhardt P, Yerkes N, O'Connor SE. Bernhardt P, et al. Org Biomol Chem. 2009 Oct 21;7(20):4166-8. doi: 10.1039/b916027m. Epub 2009 Aug 13. Org Biomol Chem. 2009. PMID: 19795053 Free PMC article.

10

Aza-tryptamine substrates in monoterpene indole alkaloid biosynthesis.

Lee HY, Yerkes N, O'Connor SE. Lee HY, et al. Chem Biol. 2009 Dec 24;16(12):1225-9. doi: 10.1016/j.chembiol.2009.11.016. Chem Biol. 2009. PMID: 20064432 Free PMC article.

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