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Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
Mazzone M, Dettori D, de Oliveira RL, Loges S, Schmidt T, Jonckx B, Tian YM, Lanahan AA, Pollard P, de Almodovar CR, De Smet F, Vinckier S, Aragonés J, Debackere K, Luttun A, Wyns S, Jordan B, Pisacane A, Gallez B, Lampugnani MG, Dejana E, Simons M, Ratcliffe P, Maxwell P, Carmeliet P. Mazzone M, et al. Among authors: lampugnani mg. Cell. 2009 Mar 6;136(5):839-851. doi: 10.1016/j.cell.2009.01.020. Epub 2009 Feb 12. Cell. 2009. PMID: 19217150 Free PMC article.
Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration.
Turowski P, Martinelli R, Crawford R, Wateridge D, Papageorgiou AP, Lampugnani MG, Gamp AC, Vestweber D, Adamson P, Dejana E, Greenwood J. Turowski P, et al. Among authors: lampugnani mg. J Cell Sci. 2008 Jan 1;121(Pt 1):29-37. doi: 10.1242/jcs.022681. J Cell Sci. 2008. PMID: 18096689 Free PMC article.
VE-cadherin is a critical endothelial regulator of TGF-beta signalling.
Rudini N, Felici A, Giampietro C, Lampugnani M, Corada M, Swirsding K, Garrè M, Liebner S, Letarte M, ten Dijke P, Dejana E. Rudini N, et al. EMBO J. 2008 Apr 9;27(7):993-1004. doi: 10.1038/emboj.2008.46. Epub 2008 Mar 13. EMBO J. 2008. PMID: 18337748 Free PMC article.
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