Gimotty PA - Search Results

1

Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor.

Anand R, Maksimoska J, Pagano N, Wong EY, Gimotty PA, Diamond SL, Meggers E, Marmorstein R. Anand R, et al. Among authors: gimotty pa. J Med Chem. 2009 Mar 26;52(6):1602-11. doi: 10.1021/jm8005806. J Med Chem. 2009. PMID: 19226137 Free PMC article.

2

PIM kinases as therapeutic targets against advanced melanoma.

Shannan B, Watters A, Chen Q, Mollin S, Dörr M, Meggers E, Xu X, Gimotty PA, Perego M, Li L, Benci J, Krepler C, Brafford P, Zhang J, Wei Z, Zhang G, Liu Q, Yin X, Nathanson KL, Herlyn M, Vultur A. Shannan B, et al. Among authors: gimotty pa. Oncotarget. 2016 Aug 23;7(34):54897-54912. doi: 10.18632/oncotarget.10703. Oncotarget. 2016. PMID: 27448973 Free PMC article.

3

PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer.

Rebecca VW, Nicastri MC, Fennelly C, Chude CI, Barber-Rotenberg JS, Ronghe A, McAfee Q, McLaughlin NP, Zhang G, Goldman AR, Ojha R, Piao S, Noguera-Ortega E, Martorella A, Alicea GM, Lee JJ, Schuchter LM, Xu X, Herlyn M, Marmorstein R, Gimotty PA, Speicher DW, Winkler JD, Amaravadi RK. Rebecca VW, et al. Among authors: gimotty pa. Cancer Discov. 2019 Feb;9(2):220-229. doi: 10.1158/2159-8290.CD-18-0706. Epub 2018 Nov 15. Cancer Discov. 2019. PMID: 30442709 Free PMC article.

4

Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K.

Villanueva J, Vultur A, Lee JT, Somasundaram R, Fukunaga-Kalabis M, Cipolla AK, Wubbenhorst B, Xu X, Gimotty PA, Kee D, Santiago-Walker AE, Letrero R, D'Andrea K, Pushparajan A, Hayden JE, Brown KD, Laquerre S, McArthur GA, Sosman JA, Nathanson KL, Herlyn M. Villanueva J, et al. Among authors: gimotty pa. Cancer Cell. 2010 Dec 14;18(6):683-95. doi: 10.1016/j.ccr.2010.11.023. Cancer Cell. 2010. PMID: 21156289 Free PMC article.

5

Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland.

Gardner HP, Belka GK, Wertheim GB, Hartman JL, Ha SI, Gimotty PA, Marquis ST, Chodosh LA. Gardner HP, et al. Among authors: gimotty pa. Development. 2000 Oct;127(20):4493-509. doi: 10.1242/dev.127.20.4493. Development. 2000. PMID: 11003847

6

Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

Kasprzycka M, Majewski M, Wang ZJ, Ptasznik A, Wysocka M, Zhang Q, Marzec M, Gimotty P, Crompton MR, Wasik MA. Kasprzycka M, et al. Am J Pathol. 2006 May;168(5):1631-41. doi: 10.2353/ajpath.2006.050521. Am J Pathol. 2006. PMID: 16651629 Free PMC article.

7

Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing.

Nagasawa T, Zhang Q, Raghunath PN, Wong HY, El-Salem M, Szallasi A, Marzec M, Gimotty P, Rook AH, Vonderheid EC, Odum N, Wasik MA. Nagasawa T, et al. Leuk Res. 2006 Mar;30(3):303-12. doi: 10.1016/j.leukres.2005.08.012. Epub 2005 Sep 26. Leuk Res. 2006. PMID: 16185764

8

MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines.

Vultur A, Villanueva J, Krepler C, Rajan G, Chen Q, Xiao M, Li L, Gimotty PA, Wilson M, Hayden J, Keeney F, Nathanson KL, Herlyn M. Vultur A, et al. Among authors: gimotty pa. Oncogene. 2014 Apr 3;33(14):1850-61. doi: 10.1038/onc.2013.131. Epub 2013 Apr 29. Oncogene. 2014. PMID: 23624919 Free PMC article.

9

Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma.

Zhang L, Huang J, Yang N, Liang S, Barchetti A, Giannakakis A, Cadungog MG, O'Brien-Jenkins A, Massobrio M, Roby KF, Katsaros D, Gimotty P, Butzow R, Weber BL, Coukos G. Zhang L, et al. Cancer Res. 2006 May 1;66(9):4627-35. doi: 10.1158/0008-5472.CAN-05-4527. Cancer Res. 2006. PMID: 16651413

10

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis.

Huang Q, Gumireddy K, Schrier M, le Sage C, Nagel R, Nair S, Egan DA, Li A, Huang G, Klein-Szanto AJ, Gimotty PA, Katsaros D, Coukos G, Zhang L, Puré E, Agami R. Huang Q, et al. Among authors: gimotty pa. Nat Cell Biol. 2008 Feb;10(2):202-10. doi: 10.1038/ncb1681. Epub 2008 Jan 13. Nat Cell Biol. 2008. PMID: 18193036

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