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NSC 622124 inhibits human Eg5 and other kinesins via interaction with the conserved microtubule-binding site.
Biochemistry. 2009 Mar 3;48(8):1754-62. doi: 10.1021/bi801291q.
Biochemistry. 2009.
PMID: 19236100
Free PMC article.
Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core.
Kim ED, Buckley R, Learman S, Richard J, Parke C, Worthylake DK, Wojcik EJ, Walker RA, Kim S.
Kim ED, et al.
J Biol Chem. 2010 Jun 11;285(24):18650-61. doi: 10.1074/jbc.M109.092072. Epub 2010 Mar 18.
J Biol Chem. 2010.
PMID: 20299460
Free PMC article.
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