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Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis.
Mathys V, Wintjens R, Lefevre P, Bertout J, Singhal A, Kiass M, Kurepina N, Wang XM, Mathema B, Baulard A, Kreiswirth BN, Bifani P. Mathys V, et al. Among authors: singhal a. Antimicrob Agents Chemother. 2009 May;53(5):2100-9. doi: 10.1128/AAC.01197-08. Epub 2009 Feb 23. Antimicrob Agents Chemother. 2009. PMID: 19237648 Free PMC article.
T cell monitoring of chemotherapy in experimental rat tuberculosis.
Foo DG, Tay HC, Siew JY, Singhal A, Camacho L, Bifani P, Dartois V, Hervé M. Foo DG, et al. Among authors: singhal a. Antimicrob Agents Chemother. 2011 Aug;55(8):3677-83. doi: 10.1128/AAC.00136-11. Epub 2011 May 31. Antimicrob Agents Chemother. 2011. PMID: 21628535 Free PMC article.
Mycobacterium tuberculosis infection induces hypoxic lung lesions in the rat.
Heng Y, Seah PG, Siew JY, Tay HC, Singhal A, Mathys V, Kiass M, Bifani P, Dartois V, Hervé M. Heng Y, et al. Among authors: singhal a. Tuberculosis (Edinb). 2011 Jul;91(4):339-41. doi: 10.1016/j.tube.2011.05.003. Epub 2011 Jun 1. Tuberculosis (Edinb). 2011. PMID: 21636324
Metformin as adjunct antituberculosis therapy.
Singhal A, Jie L, Kumar P, Hong GS, Leow MK, Paleja B, Tsenova L, Kurepina N, Chen J, Zolezzi F, Kreiswirth B, Poidinger M, Chee C, Kaplan G, Wang YT, De Libero G. Singhal A, et al. Sci Transl Med. 2014 Nov 19;6(263):263ra159. doi: 10.1126/scitranslmed.3009885. Sci Transl Med. 2014. PMID: 25411472
Mutations in genes for the F420 biosynthetic pathway and a nitroreductase enzyme are the primary resistance determinants in spontaneous in vitro-selected PA-824-resistant mutants of Mycobacterium tuberculosis.
Haver HL, Chua A, Ghode P, Lakshminarayana SB, Singhal A, Mathema B, Wintjens R, Bifani P. Haver HL, et al. Among authors: singhal a. Antimicrob Agents Chemother. 2015 Sep;59(9):5316-23. doi: 10.1128/AAC.00308-15. Epub 2015 Jun 22. Antimicrob Agents Chemother. 2015. PMID: 26100695 Free PMC article.
Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis.
Cheng CY, Gutierrez NM, Marzuki MB, Lu X, Foreman TW, Paleja B, Lee B, Balachander A, Chen J, Tsenova L, Kurepina N, Teng KWW, West K, Mehra S, Zolezzi F, Poidinger M, Kreiswirth B, Kaushal D, Kornfeld H, Newell EW, Singhal A. Cheng CY, et al. Among authors: singhal a. Sci Immunol. 2017 Mar;2(9):eaaj1789. doi: 10.1126/sciimmunol.aaj1789. Epub 2017 Mar 24. Sci Immunol. 2017. PMID: 28707004 Free PMC article.
1,425 results