Bordner J - Search Results

1

Octahydrophenanthrene-2,7-diol analogues as dissociated glucocorticoid receptor agonists: discovery and lead exploration.

Robinson RP, Buckbinder L, Haugeto AI, McNiff PA, Millham ML, Reese MR, Schaefer JF, Abramov YA, Bordner J, Chantigny YA, Kleinman EF, Laird ER, Morgan BP, Murray JC, Salter ED, Wessel MD, Yocum SA. Robinson RP, et al. Among authors: bordner j. J Med Chem. 2009 Mar 26;52(6):1731-43. doi: 10.1021/jm801512v. J Med Chem. 2009. PMID: 19239259

2

2-Aryl-3-methyloctahydrophenanthrene-2,3,7-triols as potent dissociated glucocorticoid receptor agonists.

Chantigny YA, Murray JC, Kleinman EF, Robinson RP, Plotkin MA, Reese MR, Buckbinder L, McNiff PA, Millham ML, Schaefer JF, Abramov YA, Bordner J. Chantigny YA, et al. Among authors: bordner j. J Med Chem. 2015 Mar 26;58(6):2658-77. doi: 10.1021/jm501601b. Epub 2015 Mar 17. J Med Chem. 2015. PMID: 25706100

3

Discovery of potent, nonsteroidal, and highly selective glucocorticoid receptor antagonists.

Morgan BP, Swick AG, Hargrove DM, LaFlamme JA, Moynihan MS, Carroll RS, Martin KA, Lee E, Decosta D, Bordner J. Morgan BP, et al. Among authors: bordner j. J Med Chem. 2002 Jun 6;45(12):2417-24. doi: 10.1021/jm0105530. J Med Chem. 2002. PMID: 12036351

4

Isoaromatization of 4-Alkylidene-3-oxo-1- cyclohexene-1-carboxylates. Convenient Synthesis of Methyl 4-Alkyl-3-hydroxybenzoates.

Campbell E, Martin JJ, Bordner J, Kleinman EF. Campbell E, et al. Among authors: bordner j. J Org Chem. 1996 Jul 12;61(14):4806-4809. doi: 10.1021/jo9522724. J Org Chem. 1996. PMID: 11667416 No abstract available.

5

Molecular features crucial to the activity of pyrimidine benzamide-based thrombopoietin receptor agonists.

Reiter LA, Jones CS, Brissette WH, McCurdy SP, Abramov YA, Bordner J, DiCapua FM, Munchhof MJ, Rescek DM, Samardjiev IJ, Withka JM. Reiter LA, et al. Among authors: bordner j. Bioorg Med Chem Lett. 2008 May 1;18(9):3000-6. doi: 10.1016/j.bmcl.2008.03.052. Epub 2008 Mar 20. Bioorg Med Chem Lett. 2008. PMID: 18396041

6

Structure-based design and synthesis of a potent matrix metalloproteinase-13 inhibitor based on a pyrrolidinone scaffold.

Robinson RP, Laird ER, Blake JF, Bordner J, Donahue KM, Lopresti-Morrow LL, Mitchell PG, Reese MR, Reeves LM, Stam EJ, Yocum SA. Robinson RP, et al. Among authors: bordner j. J Med Chem. 2000 Jun 15;43(12):2293-6. doi: 10.1021/jm0001368. J Med Chem. 2000. PMID: 10882354 No abstract available.

7

Striking effect of hydroxamic acid substitution on the phosphodiesterase type 4 (PDE4) and TNF alpha inhibitory activity of two series of rolipram analogues: implications for a new active site model of PDE4.

Kleinman EF, Campbell E, Giordano LA, Cohan VL, Jenkinson TH, Cheng JB, Shirley JT, Pettipher ER, Salter ED, Hibbs TA, DiCapua FM, Bordner J. Kleinman EF, et al. Among authors: bordner j. J Med Chem. 1998 Jan 29;41(3):266-70. doi: 10.1021/jm970685m. J Med Chem. 1998. PMID: 9464356 No abstract available.

8

Solid-state acid-base interactions in complexes of heterocyclic bases with dicarboxylic acids: crystallography, hydrogen bond analysis, and 15N NMR spectroscopy.

Li ZJ, Abramov Y, Bordner J, Leonard J, Medek A, Trask AV. Li ZJ, et al. Among authors: bordner j. J Am Chem Soc. 2006 Jun 28;128(25):8199-210. doi: 10.1021/ja0541332. J Am Chem Soc. 2006. PMID: 16787084

9

5-Phenyl-3-ureidobenzazepin-2-ones as cholecystokinin-B receptor antagonists.

Lowe JA 3rd, Hageman DL, Drozda SE, McLean S, Bryce DK, Crawford RT, Zorn S, Morrone J, Bordner J. Lowe JA 3rd, et al. Among authors: bordner j. J Med Chem. 1994 Oct 28;37(22):3789-811. doi: 10.1021/jm00048a015. J Med Chem. 1994. PMID: 7966138

10

(3R,4S)-3-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]chroman-4,7-diol: a conformationally restricted analogue of the NR2B subtype-selective NMDA antagonist (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)- 1-propanol.

Butler TW, Blake JF, Bordner J, Butler P, Chenard BL, Collins MA, DeCosta D, Ducat MJ, Eisenhard ME, Menniti FS, Pagnozzi MJ, Sands SB, Segelstein BE, Volberg W, White WF, Zhao D. Butler TW, et al. Among authors: bordner j. J Med Chem. 1998 Mar 26;41(7):1172-84. doi: 10.1021/jm9707986. J Med Chem. 1998. PMID: 9544217

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