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Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds.
Kampa KM, Acoba JD, Chen D, Gay J, Lee H, Beemer K, Padiernos E, Boonmark N, Zhu Z, Fan AC, Bailey AS, Fleming WH, Corless C, Felsher DW, Naumovski L, Lopez CD. Kampa KM, et al. Among authors: felsher dw. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4390-5. doi: 10.1073/pnas.0809080106. Epub 2009 Feb 26. Proc Natl Acad Sci U S A. 2009. PMID: 19251665 Free PMC article.
The human BCL6 transgene promotes the development of lymphomas in the mouse.
Baron BW, Anastasi J, Montag A, Huo D, Baron RM, Karrison T, Thirman MJ, Subudhi SK, Chin RK, Felsher DW, Fu YX, McKeithan TW, Baron JM. Baron BW, et al. Among authors: felsher dw. Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14198-203. doi: 10.1073/pnas.0406138101. Epub 2004 Sep 16. Proc Natl Acad Sci U S A. 2004. PMID: 15375218 Free PMC article.
Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch.
Giuriato S, Ryeom S, Fan AC, Bachireddy P, Lynch RC, Rioth MJ, van Riggelen J, Kopelman AM, Passegué E, Tang F, Folkman J, Felsher DW. Giuriato S, et al. Among authors: felsher dw. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16266-71. doi: 10.1073/pnas.0608017103. Epub 2006 Oct 20. Proc Natl Acad Sci U S A. 2006. PMID: 17056717 Free PMC article.
179 results