Pellecchia M - Search Results

1

Discovery of 2-(5-nitrothiazol-2-ylthio)benzo[d]thiazoles as novel c-Jun N-terminal kinase inhibitors.

De SK, Chen LH, Stebbins JL, Machleidt T, Riel-Mehan M, Dahl R, Chen V, Yuan H, Barile E, Emdadi A, Murphy R, Pellecchia M. De SK, et al. Among authors: pellecchia m. Bioorg Med Chem. 2009 Apr 1;17(7):2712-7. doi: 10.1016/j.bmc.2009.02.046. Epub 2009 Feb 26. Bioorg Med Chem. 2009. PMID: 19282190 Free PMC article.

2

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins.

Kitada S, Leone M, Sareth S, Zhai D, Reed JC, Pellecchia M. Kitada S, et al. Among authors: pellecchia m. J Med Chem. 2003 Sep 25;46(20):4259-64. doi: 10.1021/jm030190z. J Med Chem. 2003. PMID: 13678404

3

Discovery of a novel class of reversible non-peptide caspase inhibitors via a structure-based approach.

Fattorusso R, Jung D, Crowell KJ, Forino M, Pellecchia M. Fattorusso R, et al. Among authors: pellecchia m. J Med Chem. 2005 Mar 10;48(5):1649-56. doi: 10.1021/jm0493212. J Med Chem. 2005. PMID: 15743206

4

Virtual docking approaches to protein kinase B inhibition.

Forino M, Jung D, Easton JB, Houghton PJ, Pellecchia M. Forino M, et al. Among authors: pellecchia m. J Med Chem. 2005 Apr 7;48(7):2278-81. doi: 10.1021/jm048962u. J Med Chem. 2005. PMID: 15801821

5

Efficient synthetic inhibitors of anthrax lethal factor.

Forino M, Johnson S, Wong TY, Rozanov DV, Savinov AY, Li W, Fattorusso R, Becattini B, Orry AJ, Jung D, Abagyan RA, Smith JW, Alibek K, Liddington RC, Strongin AY, Pellecchia M. Forino M, et al. Among authors: pellecchia m. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9499-504. doi: 10.1073/pnas.0502733102. Epub 2005 Jun 27. Proc Natl Acad Sci U S A. 2005. PMID: 15983377 Free PMC article.

6

SAR by ILOEs: an NMR-based approach to reverse chemical genetics.

Becattini B, Pellecchia M. Becattini B, et al. Among authors: pellecchia m. Chemistry. 2006 Mar 20;12(10):2658-62. doi: 10.1002/chem.200500636. Chemistry. 2006. PMID: 16121405

7

Anthrax lethal factor protease inhibitors: synthesis, SAR, and structure-based 3D QSAR studies.

Johnson SL, Jung D, Forino M, Chen Y, Satterthwait A, Rozanov DV, Strongin AY, Pellecchia M. Johnson SL, et al. Among authors: pellecchia m. J Med Chem. 2006 Jan 12;49(1):27-30. doi: 10.1021/jm050892j. J Med Chem. 2006. PMID: 16392787 Free PMC article.

8

A structure-based approach to retinoid X receptor-alpha inhibition.

Stebbins JL, Jung D, Leone M, Zhang XK, Pellecchia M. Stebbins JL, et al. Among authors: pellecchia m. J Biol Chem. 2006 Jun 16;281(24):16643-8. doi: 10.1074/jbc.M600318200. Epub 2006 Apr 10. J Biol Chem. 2006. PMID: 16606625 Free article.

9

Robust lanthanide-based assays for the detection of anti-apoptotic Bcl-2-family protein antagonists.

Rega MF, Reed JC, Pellecchia M. Rega MF, et al. Among authors: pellecchia m. Bioorg Chem. 2007 Apr;35(2):113-20. doi: 10.1016/j.bioorg.2006.07.006. Epub 2006 Sep 22. Bioorg Chem. 2007. PMID: 16996562

10

A high-throughput screening approach to anthrax lethal factor inhibition.

Johnson SL, Chen LH, Pellecchia M. Johnson SL, et al. Among authors: pellecchia m. Bioorg Chem. 2007 Aug;35(4):306-12. doi: 10.1016/j.bioorg.2006.12.005. Epub 2007 Feb 22. Bioorg Chem. 2007. PMID: 17320146 Free PMC article.

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