Kastrup JS - Search Results

1

Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine.

Frydenvang K, Lash LL, Naur P, Postila PA, Pickering DS, Smith CM, Gajhede M, Sasaki M, Sakai R, Pentikaïnen OT, Swanson GT, Kastrup JS. Frydenvang K, et al. Among authors: kastrup js. J Biol Chem. 2009 May 22;284(21):14219-29. doi: 10.1074/jbc.M808547200. Epub 2009 Mar 18. J Biol Chem. 2009. PMID: 19297335 Free PMC article.

2

Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane.

Geisler C, Dietrich J, Nielsen BL, Kastrup J, Lauritsen JP, Odum N, Christensen MD. Geisler C, et al. J Biol Chem. 1998 Aug 14;273(33):21316-23. doi: 10.1074/jbc.273.33.21316. J Biol Chem. 1998. PMID: 9694892 Free article.

3

Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core.

Hogner A, Kastrup JS, Jin R, Liljefors T, Mayer ML, Egebjerg J, Larsen IK, Gouaux E. Hogner A, et al. Among authors: kastrup js. J Mol Biol. 2002 Sep 6;322(1):93-109. doi: 10.1016/s0022-2836(02)00650-2. J Mol Biol. 2002. PMID: 12215417

4

GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists.

Kasper C, Lunn ML, Liljefors T, Gouaux E, Egebjerg J, Kastrup JS. Kasper C, et al. Among authors: kastrup js. FEBS Lett. 2002 Nov 6;531(2):173-8. doi: 10.1016/s0014-5793(02)03496-8. FEBS Lett. 2002. PMID: 12417307 Free article.

5

Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX.

Hogner A, Greenwood JR, Liljefors T, Lunn ML, Egebjerg J, Larsen IK, Gouaux E, Kastrup JS. Hogner A, et al. Among authors: kastrup js. J Med Chem. 2003 Jan 16;46(2):214-21. doi: 10.1021/jm020989v. J Med Chem. 2003. PMID: 12519060

6

Three-dimensional structure of the ligand-binding core of GluR2 in complex with the agonist (S)-ATPA: implications for receptor subunit selectivity.

Lunn ML, Hogner A, Stensbøl TB, Gouaux E, Egebjerg J, Kastrup JS. Lunn ML, et al. Among authors: kastrup js. J Med Chem. 2003 Feb 27;46(5):872-5. doi: 10.1021/jm021020+. J Med Chem. 2003. PMID: 12593667

7

Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis.

Sprogøe D, van den Broek LA, Mirza O, Kastrup JS, Voragen AG, Gajhede M, Skov LK. Sprogøe D, et al. Among authors: kastrup js. Biochemistry. 2004 Feb 10;43(5):1156-62. doi: 10.1021/bi0356395. Biochemistry. 2004. PMID: 14756551

8

Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1.

Kulahin N, Kasper C, Gajhede M, Berezin V, Bock E, Kastrup JS. Kulahin N, et al. Among authors: kastrup js. Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):591-3. doi: 10.1107/S0907444904001167. Epub 2004 Feb 25. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 14993704

9

Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family.

Kristensen O, Laurberg M, Liljas A, Kastrup JS, Gajhede M. Kristensen O, et al. Among authors: kastrup js. Biochemistry. 2004 Jul 20;43(28):8894-900. doi: 10.1021/bi049083c. Biochemistry. 2004. PMID: 15248747

10

Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2.

Frandsen A, Pickering DS, Vestergaard B, Kasper C, Nielsen BB, Greenwood JR, Campiani G, Fattorusso C, Gajhede M, Schousboe A, Kastrup JS. Frandsen A, et al. Among authors: kastrup js. Mol Pharmacol. 2005 Mar;67(3):703-13. doi: 10.1124/mol.104.002931. Epub 2004 Dec 9. Mol Pharmacol. 2005. PMID: 15591246

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