Luedtke RR - Search Results

1

N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists.

Newman AH, Grundt P, Cyriac G, Deschamps JR, Taylor M, Kumar R, Ho D, Luedtke RR. Newman AH, et al. Among authors: luedtke rr. J Med Chem. 2009 Apr 23;52(8):2559-70. doi: 10.1021/jm900095y. J Med Chem. 2009. PMID: 19331412 Free PMC article.

2

Synthesis and structure-activity relationships of naphthamides as dopamine D3 receptor ligands.

Huang Y, Luedtke RR, Freeman RA, Wu L, Mach RH. Huang Y, et al. Among authors: luedtke rr. J Med Chem. 2001 May 24;44(11):1815-26. doi: 10.1021/jm0100077. J Med Chem. 2001. PMID: 11356115

3

N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists.

Newman AH, Cao J, Bennett CJ, Robarge MJ, Freeman RA, Luedtke RR. Newman AH, et al. Among authors: luedtke rr. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2179-83. doi: 10.1016/s0960-894x(03)00389-5. Bioorg Med Chem Lett. 2003. PMID: 12798330

4

Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands.

Mach RH, Huang Y, Freeman RA, Wu L, Vangveravong S, Luedtke RR. Mach RH, et al. Among authors: luedtke rr. Bioorg Med Chem Lett. 2004 Jan 5;14(1):195-202. doi: 10.1016/j.bmcl.2003.09.083. Bioorg Med Chem Lett. 2004. PMID: 14684327

5

Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.

Chu W, Tu Z, McElveen E, Xu J, Taylor M, Luedtke RR, Mach RH. Chu W, et al. Among authors: luedtke rr. Bioorg Med Chem. 2005 Jan 3;13(1):77-87. doi: 10.1016/j.bmc.2004.09.054. Bioorg Med Chem. 2005. PMID: 15582454

6

Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor.

Grundt P, Carlson EE, Cao J, Bennett CJ, McElveen E, Taylor M, Luedtke RR, Newman AH. Grundt P, et al. Among authors: luedtke rr. J Med Chem. 2005 Feb 10;48(3):839-48. doi: 10.1021/jm049465g. J Med Chem. 2005. PMID: 15689168

7

Synthesis and characterization of selective dopamine D2 receptor antagonists.

Vangveravong S, McElveen E, Taylor M, Xu J, Tu Z, Luedtke RR, Mach RH. Vangveravong S, et al. Among authors: luedtke rr. Bioorg Med Chem. 2006 Feb 1;14(3):815-25. doi: 10.1016/j.bmc.2005.09.008. Epub 2005 Nov 8. Bioorg Med Chem. 2006. PMID: 16288878

8

Analogues of the dopamine D2 receptor antagonist L741,626: Binding, function, and SAR.

Grundt P, Husband SL, Luedtke RR, Taylor M, Newman AH. Grundt P, et al. Among authors: luedtke rr. Bioorg Med Chem Lett. 2007 Feb 1;17(3):745-9. doi: 10.1016/j.bmcl.2006.10.076. Epub 2006 Oct 28. Bioorg Med Chem Lett. 2007. PMID: 17095222 Free PMC article.

9

Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents.

Grundt P, Prevatt KM, Cao J, Taylor M, Floresca CZ, Choi JK, Jenkins BG, Luedtke RR, Newman AH. Grundt P, et al. Among authors: luedtke rr. J Med Chem. 2007 Aug 23;50(17):4135-46. doi: 10.1021/jm0704200. Epub 2007 Aug 2. J Med Chem. 2007. PMID: 17672446

10

Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol.

Paul NM, Taylor M, Kumar R, Deschamps JR, Luedtke RR, Newman AH. Paul NM, et al. Among authors: luedtke rr. J Med Chem. 2008 Oct 9;51(19):6095-109. doi: 10.1021/jm800532x. Epub 2008 Sep 6. J Med Chem. 2008. PMID: 18774793 Free PMC article.

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