Meegan MJ - Search Results

1

Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin.

Knox AJ, Price T, Pawlak M, Golfis G, Flood CT, Fayne D, Williams DC, Meegan MJ, Lloyd DG. Knox AJ, et al. Among authors: meegan mj. J Med Chem. 2009 Apr 23;52(8):2177-80. doi: 10.1021/jm801569z. J Med Chem. 2009. PMID: 19331414

2

Flexible estrogen receptor modulators: design, synthesis, and antagonistic effects in human MCF-7 breast cancer cells.

Meegan MJ, Hughes RB, Lloyd DG, Williams DC, Zisterer DM. Meegan MJ, et al. J Med Chem. 2001 Mar 29;44(7):1072-84. doi: 10.1021/jm001119l. J Med Chem. 2001. PMID: 11297454

3

Ethyl side-chain modifications in novel flexible antiestrogens--design, synthesis and biological efficacy in assay against the MCF-7 breast tumor cell line.

Meegan MJ, Hughes RB, Lloyd DG, Williams DC, Zisterer DM. Meegan MJ, et al. Anticancer Drug Des. 2001 Feb;16(1):57-69. Anticancer Drug Des. 2001. PMID: 11762645

4

Advances in the science of estrogen receptor modulation.

Meegan MJ, Lloyd DG. Meegan MJ, et al. Curr Med Chem. 2003 Feb;10(3):181-210. doi: 10.2174/0929867033368501. Curr Med Chem. 2003. PMID: 12570707 Review.

5

Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor.

Lloyd DG, Hughes RB, Zisterer DM, Williams DC, Fattorusso C, Catalanotti B, Campiani G, Meegan MJ. Lloyd DG, et al. Among authors: meegan mj. J Med Chem. 2004 Nov 4;47(23):5612-5. doi: 10.1021/jm0495834. J Med Chem. 2004. PMID: 15509159

6

Recent advances in estrogen receptor antagonists.

Lloyd DG, Meegan MJ. Lloyd DG, et al. Among authors: meegan mj. IDrugs. 2000 Jun;3(6):632-42. IDrugs. 2000. PMID: 16096926 No abstract available.

7

Considerations in compound database preparation--"hidden" impact on virtual screening results.

Knox AJ, Meegan MJ, Carta G, Lloyd DG. Knox AJ, et al. Among authors: meegan mj. J Chem Inf Model. 2005 Nov-Dec;45(6):1908-19. doi: 10.1021/ci050185z. J Chem Inf Model. 2005. PMID: 16309298

8

Estrogen receptors: molecular interactions, virtual screening and future prospects.

Knox AJ, Meegan MJ, Lloyd DG. Knox AJ, et al. Among authors: meegan mj. Curr Top Med Chem. 2006;6(3):217-43. doi: 10.2174/156802606776173438. Curr Top Med Chem. 2006. PMID: 16515479 Review.

9

Oncology exploration: charting cancer medicinal chemistry space.

Lloyd DG, Golfis G, Knox AJ, Fayne D, Meegan MJ, Oprea TI. Lloyd DG, et al. Among authors: meegan mj. Drug Discov Today. 2006 Feb;11(3-4):149-59. doi: 10.1016/S1359-6446(05)03688-3. Drug Discov Today. 2006. PMID: 16533713 Review.

10

Antiestrogenically active 2-benzyl-1,1-diarylbut-2-enes: synthesis, structure-activity relationships and molecular modeling study for flexible estrogen receptor antagonists.

Lloyd DG, Smith HM, O'Sullivan T, Knox AS, Zisterer DM, Meegan MJ. Lloyd DG, et al. Among authors: meegan mj. Med Chem. 2006 Mar;2(2):147-68. doi: 10.2174/157340606776056142. Med Chem. 2006. PMID: 16787364

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