Pawlak M - Search Results

1

Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin.

Knox AJ, Price T, Pawlak M, Golfis G, Flood CT, Fayne D, Williams DC, Meegan MJ, Lloyd DG. Knox AJ, et al. Among authors: pawlak m. J Med Chem. 2009 Apr 23;52(8):2177-80. doi: 10.1021/jm801569z. J Med Chem. 2009. PMID: 19331414

2

General molecular biology and architecture of nuclear receptors.

Pawlak M, Lefebvre P, Staels B. Pawlak M, et al. Curr Top Med Chem. 2012;12(6):486-504. doi: 10.2174/156802612799436641. Curr Top Med Chem. 2012. PMID: 22242852 Free PMC article. Review.

3

The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors.

Flajollet S, Rachez C, Ploton M, Schulz C, Gallais R, Métivier R, Pawlak M, Leray A, Issulahi AA, Héliot L, Staels B, Salbert G, Lefebvre P. Flajollet S, et al. Among authors: pawlak m. PLoS One. 2013 Jun 10;8(6):e64880. doi: 10.1371/journal.pone.0064880. Print 2013. PLoS One. 2013. PMID: 23762261 Free PMC article.

4

The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice.

Pawlak M, Baugé E, Bourguet W, De Bosscher K, Lalloyer F, Tailleux A, Lebherz C, Lefebvre P, Staels B. Pawlak M, et al. Hepatology. 2014 Nov;60(5):1593-606. doi: 10.1002/hep.27297. Epub 2014 Oct 1. Hepatology. 2014. PMID: 24995693

5

Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease.

Pawlak M, Lefebvre P, Staels B. Pawlak M, et al. J Hepatol. 2015 Mar;62(3):720-33. doi: 10.1016/j.jhep.2014.10.039. Epub 2014 Nov 1. J Hepatol. 2015. PMID: 25450203 Free article. Review.

6

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD.

Gross B, Pawlak M, Lefebvre P, Staels B. Gross B, et al. Among authors: pawlak m. Nat Rev Endocrinol. 2017 Jan;13(1):36-49. doi: 10.1038/nrendo.2016.135. Epub 2016 Sep 16. Nat Rev Endocrinol. 2017. PMID: 27636730 Review.

7

Ketone Body Therapy Protects From Lipotoxicity and Acute Liver Failure Upon Pparα Deficiency.

Pawlak M, Baugé E, Lalloyer F, Lefebvre P, Staels B. Pawlak M, et al. Mol Endocrinol. 2015 Aug;29(8):1134-43. doi: 10.1210/me.2014-1383. Epub 2015 Jun 18. Mol Endocrinol. 2015. PMID: 26087172 Free PMC article.

8

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα.

Ratman D, Mylka V, Bougarne N, Pawlak M, Caron S, Hennuyer N, Paumelle R, De Cauwer L, Thommis J, Rider MH, Libert C, Lievens S, Tavernier J, Staels B, De Bosscher K. Ratman D, et al. Among authors: pawlak m. Nucleic Acids Res. 2016 Dec 15;44(22):10539-10553. doi: 10.1093/nar/gkw742. Epub 2016 Aug 30. Nucleic Acids Res. 2016. PMID: 27576532 Free PMC article.

9

Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin.

Lefebvre P, Lalloyer F, Baugé E, Pawlak M, Gheeraert C, Dehondt H, Vanhoutte J, Woitrain E, Hennuyer N, Mazuy C, Bobowski-Gérard M, Zummo FP, Derudas B, Driessen A, Hubens G, Vonghia L, Kwanten WJ, Michielsen P, Vanwolleghem T, Eeckhoute J, Verrijken A, Van Gaal L, Francque S, Staels B. Lefebvre P, et al. Among authors: pawlak m. JCI Insight. 2017 Jul 6;2(13):e92264. doi: 10.1172/jci.insight.92264. eCollection 2017 Jul 6. JCI Insight. 2017. PMID: 28679947 Free PMC article.

10

Protein kinase C delta is a critical regulator of CD1d-mediated antigen presentation.

Brutkiewicz RR, Willard CA, Gillett-Heacock KK, Pawlak MR, Bailey JC, Khan MA, Nagala M, Du W, Gervay-Hague J, Renukaradhya GJ. Brutkiewicz RR, et al. Among authors: pawlak mr. Eur J Immunol. 2007 Sep;37(9):2390-5. doi: 10.1002/eji.200737124. Eur J Immunol. 2007. PMID: 17705133 Free article.

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