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PRMT5 Inhibition Reduces Hyperinflammation in a Murine Model of Secondary Hemophagocytic Lymphohistiocytosis (HLH).
Brown-Burke F, Saadey R, Mao HCC, Marra P, Brooks E, Wandtke A, Hout I, Leon S, Sharma A, Yasin A, Cash T, Ahmed EH, Baiocchi EJ, Finoti SS, Zhang X, Bhagwat N, Vaddi K, Scherle P, Mozhenkova A, El-Ayachi I, Schenk AD, Sloan SL, Whitman K, Helmig-Mason J, Steyn S, Klimaszewski HL, Weist J, Weigel C, Koirala S, Alinari L, Snyder K, Ranganathan P, Chen CJ, Jordan MB, Baiocchi RA, Shindiapina P. Brown-Burke F, et al. Among authors: el ayachi i. Blood Adv. 2025 Jan 18:bloodadvances.2024013651. doi: 10.1182/bloodadvances.2024013651. Online ahead of print. Blood Adv. 2025. PMID: 39825858
Simultaneous Multi-Organ Metastases from Chemo-Resistant Triple-Negative Breast Cancer Are Prevented by Interfering with WNT-Signaling.
Fatima I, El-Ayachi I, Playa HC, Alva-Ornelas JA, Khalid AB, Kuenzinger WL, Wend P, Pence JC, Brakefield L, Krutilina RI, Johnson DL, O'Regan RM, Seewaldt V, Seagroves TN, Krum SA, Miranda-Carboni GA. Fatima I, et al. Among authors: el ayachi i. Cancers (Basel). 2019 Dec 17;11(12):2039. doi: 10.3390/cancers11122039. Cancers (Basel). 2019. PMID: 31861131 Free PMC article.
Mechanistic Insight on the Mode of Action of Colletoic Acid.
Ling T, Miller DJ, Lang WH, Griffith E, Rodriguez-Cortes A, El Ayachi I, Palacios G, Min J, Miranda-Carboni G, Lee RE, Rivas F. Ling T, et al. Among authors: el ayachi i. J Med Chem. 2019 Aug 8;62(15):6925-6940. doi: 10.1021/acs.jmedchem.9b00187. Epub 2019 Jul 24. J Med Chem. 2019. PMID: 31294974 Free PMC article.
The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer.
El Ayachi I, Fatima I, Wend P, Alva-Ornelas JA, Runke S, Kuenzinger WL, Silva J, Silva W, Gray JK, Lehr S, Barch HC, Krutilina RI, White AC, Cardiff R, Yee LD, Yang L, O'Regan RM, Lowry WE, Seagroves TN, Seewaldt V, Krum SA, Miranda-Carboni GA. El Ayachi I, et al. Cancer Res. 2019 Mar 1;79(5):982-993. doi: 10.1158/0008-5472.CAN-18-1069. Epub 2018 Dec 18. Cancer Res. 2019. PMID: 30563890 Free PMC article.
16 results