van der Valk MA - Search Results

1

Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors.

Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akçakaya P, Löwik CW, Fodde R, Wit JM, Robanus-Maandag EC. Miclea RL, et al. Among authors: van der valk ma. BMC Dev Biol. 2009 Apr 8;9:26. doi: 10.1186/1471-213X-9-26. BMC Dev Biol. 2009. PMID: 19356224 Free PMC article.

2

A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.

Gaspar C, Franken P, Molenaar L, Breukel C, van der Valk M, Smits R, Fodde R. Gaspar C, et al. PLoS Genet. 2009 Jul;5(7):e1000547. doi: 10.1371/journal.pgen.1000547. Epub 2009 Jul 3. PLoS Genet. 2009. PMID: 19578404 Free PMC article.

3

β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis.

van Veelen W, Le NH, Helvensteijn W, Blonden L, Theeuwes M, Bakker ER, Franken PF, van Gurp L, Meijlink F, van der Valk MA, Kuipers EJ, Fodde R, Smits R. van Veelen W, et al. Among authors: van der valk ma. Gut. 2011 Sep;60(9):1204-12. doi: 10.1136/gut.2010.233460. Epub 2011 Feb 9. Gut. 2011. PMID: 21307168 Free PMC article.

4

In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3.

Jonkers J, van Amerongen R, van der Valk M, Robanus-Maandag E, Molenaar M, Destrée O, Berns A. Jonkers J, et al. Mech Dev. 1999 Nov;88(2):183-94. doi: 10.1016/s0925-4773(99)00187-2. Mech Dev. 1999. PMID: 10534617 Free article.

5

Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin.

Robanus-Maandag E, Giovannini M, van der Valk M, Niwa-Kawakita M, Abramowski V, Antonescu C, Thomas G, Berns A. Robanus-Maandag E, et al. Oncogene. 2004 Aug 26;23(39):6541-7. doi: 10.1038/sj.onc.1207858. Oncogene. 2004. PMID: 15221010

6

Smad4 haploinsufficiency in mouse models for intestinal cancer.

Alberici P, Jagmohan-Changur S, De Pater E, Van Der Valk M, Smits R, Hohenstein P, Fodde R. Alberici P, et al. Oncogene. 2006 Mar 23;25(13):1841-51. doi: 10.1038/sj.onc.1209226. Oncogene. 2006. PMID: 16288217

7

p107 is a suppressor of retinoblastoma development in pRb-deficient mice.

Robanus-Maandag E, Dekker M, van der Valk M, Carrozza ML, Jeanny JC, Dannenberg JH, Berns A, te Riele H. Robanus-Maandag E, et al. Genes Dev. 1998 Jun 1;12(11):1599-609. doi: 10.1101/gad.12.11.1599. Genes Dev. 1998. PMID: 9620848 Free PMC article.

8

Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice.

Bakker ER, Raghoebir L, Franken PF, Helvensteijn W, van Gurp L, Meijlink F, van der Valk MA, Rottier RJ, Kuipers EJ, van Veelen W, Smits R. Bakker ER, et al. Among authors: van der valk ma. Dev Biol. 2012 Sep 1;369(1):91-100. doi: 10.1016/j.ydbio.2012.06.007. Epub 2012 Jun 9. Dev Biol. 2012. PMID: 22691362 Free article.

9

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.

Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, Mol CA, van der Valk MA, Robanus-Maandag EC, te Riele HP, et al. Schinkel AH, et al. Among authors: van deemter l, van tellingen o, van der valk ma. Cell. 1994 May 20;77(4):491-502. doi: 10.1016/0092-8674(94)90212-7. Cell. 1994. PMID: 7910522

10

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.

van der Lugt NM, Domen J, Linders K, van Roon M, Robanus-Maandag E, te Riele H, van der Valk M, Deschamps J, Sofroniew M, van Lohuizen M, et al. van der Lugt NM, et al. Genes Dev. 1994 Apr 1;8(7):757-69. doi: 10.1101/gad.8.7.757. Genes Dev. 1994. PMID: 7926765 Free article.

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