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Artemin is oncogenic for human mammary carcinoma cells.
Kang J, Perry JK, Pandey V, Fielder GC, Mei B, Qian PX, Wu ZS, Zhu T, Liu DX, Lobie PE. Kang J, et al. Among authors: qian px. Oncogene. 2009 May 14;28(19):2034-45. doi: 10.1038/onc.2009.66. Epub 2009 Apr 13. Oncogene. 2009. PMID: 19363524
Artemin, a member of the glial cell line-derived neurotrophic factor family of ligands, is HER2-regulated and mediates acquired trastuzumab resistance by promoting cancer stem cell-like behavior in mammary carcinoma cells.
Ding K, Banerjee A, Tan S, Zhao J, Zhuang Q, Li R, Qian P, Liu S, Wu ZS, Lobie PE, Zhu T. Ding K, et al. J Biol Chem. 2014 Jun 6;289(23):16057-71. doi: 10.1074/jbc.M113.529552. Epub 2014 Apr 15. J Biol Chem. 2014. PMID: 24737320 Free PMC article.
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