Klaassen CD - Search Results

1

CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes.

Reisman SA, Buckley DB, Tanaka Y, Klaassen CD. Reisman SA, et al. Among authors: klaassen cd. Toxicol Appl Pharmacol. 2009 Apr 1;236(1):109-14. doi: 10.1016/j.taap.2008.12.024. Epub 2009 Jan 20. Toxicol Appl Pharmacol. 2009. PMID: 19371629 Free PMC article.

2

Hepatic ischemia-reperfusion induces renal heme oxygenase-1 via NF-E2-related factor 2 in rats and mice.

Tanaka Y, Maher JM, Chen C, Klaassen CD. Tanaka Y, et al. Among authors: klaassen cd. Mol Pharmacol. 2007 Mar;71(3):817-25. doi: 10.1124/mol.106.029033. Epub 2006 Dec 6. Mol Pharmacol. 2007. PMID: 17151289

3

Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity.

Tanaka Y, Aleksunes LM, Goedken MJ, Chen C, Reisman SA, Manautou JE, Klaassen CD. Tanaka Y, et al. Among authors: klaassen cd. Toxicol Appl Pharmacol. 2008 Sep 15;231(3):364-73. doi: 10.1016/j.taap.2008.05.022. Epub 2008 Jul 9. Toxicol Appl Pharmacol. 2008. PMID: 18617210 Free PMC article.

4

Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice.

Gyamfi MA, Tanaka Y, He L, Klaassen CD, Wan YJ. Gyamfi MA, et al. Among authors: klaassen cd. Toxicol Appl Pharmacol. 2009 Jan 15;234(2):166-78. doi: 10.1016/j.taap.2008.09.022. Epub 2008 Oct 8. Toxicol Appl Pharmacol. 2009. PMID: 18952117 Free PMC article.

5

Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species.

Reisman SA, Yeager RL, Yamamoto M, Klaassen CD. Reisman SA, et al. Among authors: klaassen cd. Toxicol Sci. 2009 Mar;108(1):35-47. doi: 10.1093/toxsci/kfn267. Epub 2009 Jan 6. Toxicol Sci. 2009. PMID: 19129213 Free PMC article.

6

ANIT-induced intrahepatic cholestasis alters hepatobiliary transporter expression via Nrf2-dependent and independent signaling.

Tanaka Y, Aleksunes LM, Cui YJ, Klaassen CD. Tanaka Y, et al. Among authors: klaassen cd. Toxicol Sci. 2009 Apr;108(2):247-57. doi: 10.1093/toxsci/kfp020. Epub 2009 Jan 29. Toxicol Sci. 2009. PMID: 19181614 Free PMC article.

7

Nrf2 activation enhances biliary excretion of sulfobromophthalein by inducing glutathione-S-transferase activity.

Reisman SA, Csanaky IL, Yeager RL, Klaassen CD. Reisman SA, et al. Among authors: klaassen cd. Toxicol Sci. 2009 May;109(1):24-30. doi: 10.1093/toxsci/kfp045. Epub 2009 Feb 26. Toxicol Sci. 2009. PMID: 19246623 Free PMC article.

8

Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice.

Reisman SA, Csanaky IL, Aleksunes LM, Klaassen CD. Reisman SA, et al. Among authors: klaassen cd. Toxicol Sci. 2009 May;109(1):31-40. doi: 10.1093/toxsci/kfp047. Epub 2009 Feb 26. Toxicol Sci. 2009. PMID: 19246624 Free PMC article.

9

Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes.

Reisman SA, Aleksunes LM, Klaassen CD. Reisman SA, et al. Among authors: klaassen cd. Biochem Pharmacol. 2009 Apr 1;77(7):1273-82. doi: 10.1016/j.bcp.2008.12.028. Biochem Pharmacol. 2009. PMID: 19283895 Free PMC article.

10

Introducing the "TCDD-inducible AhR-Nrf2 gene battery".

Yeager RL, Reisman SA, Aleksunes LM, Klaassen CD. Yeager RL, et al. Among authors: klaassen cd. Toxicol Sci. 2009 Oct;111(2):238-46. doi: 10.1093/toxsci/kfp115. Epub 2009 May 27. Toxicol Sci. 2009. PMID: 19474220 Free PMC article.

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