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Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity.
Amthor H, Otto A, Vulin A, Rochat A, Dumonceaux J, Garcia L, Mouisel E, Hourdé C, Macharia R, Friedrichs M, Relaix F, Zammit PS, Matsakas A, Patel K, Partridge T. Amthor H, et al. Among authors: otto a. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7479-84. doi: 10.1073/pnas.0811129106. Epub 2009 Apr 21. Proc Natl Acad Sci U S A. 2009. PMID: 19383783 Free PMC article.
Lack of myostatin results in excessive muscle growth but impaired force generation.
Amthor H, Macharia R, Navarrete R, Schuelke M, Brown SC, Otto A, Voit T, Muntoni F, Vrbóva G, Partridge T, Zammit P, Bunger L, Patel K. Amthor H, et al. Among authors: otto a. Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1835-40. doi: 10.1073/pnas.0604893104. Epub 2007 Jan 31. Proc Natl Acad Sci U S A. 2007. PMID: 17267614 Free PMC article.
Axon and muscle spindle hyperplasia in the myostatin null mouse.
Elashry MI, Otto A, Matsakas A, El-Morsy SE, Jones L, Anderson B, Patel K. Elashry MI, et al. Among authors: otto a. J Anat. 2011 Feb;218(2):173-84. doi: 10.1111/j.1469-7580.2010.01327.x. J Anat. 2011. PMID: 21208206 Free PMC article.
834 results