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IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes : JAKinibs suppress the interferon response in RA-FLSs.
Bonelli M, Dalwigk K, Platzer A, Olmos Calvo I, Hayer S, Niederreiter B, Holinka J, Sevelda F, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP, Karonitsch T. Bonelli M, et al. Among authors: dalwigk k. Exp Mol Med. 2019 Jul 8;51(7):1-11. doi: 10.1038/s12276-019-0267-6. Exp Mol Med. 2019. PMID: 31285419 Free PMC article.
mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation.
Karonitsch T, Kandasamy RK, Kartnig F, Herdy B, Dalwigk K, Niederreiter B, Holinka J, Sevelda F, Windhager R, Bilban M, Weichhart T, Säemann M, Pap T, Steiner G, Smolen JS, Kiener HP, Superti-Furga G. Karonitsch T, et al. Among authors: dalwigk k. Cell Rep. 2018 May 15;23(7):2157-2167. doi: 10.1016/j.celrep.2018.04.044. Cell Rep. 2018. PMID: 29768212 Free PMC article.
FOXO3 is involved in the tumor necrosis factor-driven inflammatory response in fibroblast-like synoviocytes.
Brandstetter B, Dalwigk K, Platzer A, Niederreiter B, Kartnig F, Fischer A, Vladimer GI, Byrne RA, Sevelda F, Holinka J, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP, Karonitsch T. Brandstetter B, et al. Among authors: dalwigk k. Lab Invest. 2019 May;99(5):648-658. doi: 10.1038/s41374-018-0184-7. Epub 2019 Jan 24. Lab Invest. 2019. PMID: 30679758 Free article.
TNFR2 is critical for TNF-induced rheumatoid arthritis fibroblast-like synoviocyte inflammation.
Suto T, Tosevska A, Dalwigk K, Kugler M, Dellinger M, Stanic I, Platzer A, Niederreiter B, Sevelda F, Bonelli M, Pap T, Kiener H, Okamura K, Chikuda H, Aletaha D, Heinz LX, Karonitsch T. Suto T, et al. Among authors: dalwigk k. Rheumatology (Oxford). 2022 Nov 2;61(11):4535-4546. doi: 10.1093/rheumatology/keac124. Rheumatology (Oxford). 2022. PMID: 35258553