Einholm AP - Search Results

1

The C terminus of Na+,K+-ATPase controls Na+ affinity on both sides of the membrane through Arg935.

Toustrup-Jensen MS, Holm R, Einholm AP, Schack VR, Morth JP, Nissen P, Andersen JP, Vilsen B. Toustrup-Jensen MS, et al. Among authors: einholm ap. J Biol Chem. 2009 Jul 10;284(28):18715-25. doi: 10.1074/jbc.M109.015099. Epub 2009 May 5. J Biol Chem. 2009. PMID: 19416970 Free PMC article.

2

Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease.

Toustrup-Jensen MS, Einholm AP, Schack VR, Nielsen HN, Holm R, Sobrido MJ, Andersen JP, Clausen T, Vilsen B. Toustrup-Jensen MS, et al. Among authors: einholm ap. J Biol Chem. 2014 Feb 7;289(6):3186-97. doi: 10.1074/jbc.M113.543272. Epub 2013 Dec 19. J Biol Chem. 2014. PMID: 24356962 Free PMC article.

3

Rescue of Na+ affinity in aspartate 928 mutants of Na+,K+-ATPase by secondary mutation of glutamate 314.

Holm R, Einholm AP, Andersen JP, Vilsen B. Holm R, et al. Among authors: einholm ap. J Biol Chem. 2015 Apr 10;290(15):9801-11. doi: 10.1074/jbc.M114.625509. Epub 2015 Feb 24. J Biol Chem. 2015. PMID: 25713066 Free PMC article.

4

Importance of a Potential Protein Kinase A Phosphorylation Site of Na+,K+-ATPase and Its Interaction Network for Na+ Binding.

Einholm AP, Nielsen HN, Holm R, Toustrup-Jensen MS, Vilsen B. Einholm AP, et al. J Biol Chem. 2016 May 13;291(20):10934-47. doi: 10.1074/jbc.M115.701201. Epub 2016 Mar 24. J Biol Chem. 2016. PMID: 27013656 Free PMC article.

5

Neurological disease mutations of α3 Na⁺,K⁺-ATPase: Structural and functional perspectives and rescue of compromised function.

Holm R, Toustrup-Jensen MS, Einholm AP, Schack VR, Andersen JP, Vilsen B. Holm R, et al. Among authors: einholm ap. Biochim Biophys Acta. 2016 Nov;1857(11):1807-1828. doi: 10.1016/j.bbabio.2016.08.009. Epub 2016 Aug 28. Biochim Biophys Acta. 2016. PMID: 27577505 Free article. Review.

6

Arginine substitution of a cysteine in transmembrane helix M8 converts Na+,K+-ATPase to an electroneutral pump similar to H+,K+-ATPase.

Holm R, Khandelwal J, Einholm AP, Andersen JP, Artigas P, Vilsen B. Holm R, et al. Among authors: einholm ap. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):316-321. doi: 10.1073/pnas.1617951114. Epub 2016 Dec 27. Proc Natl Acad Sci U S A. 2017. PMID: 28028214 Free PMC article.

7

Distinct effects of Q925 mutation on intracellular and extracellular Na⁺ and K⁺ binding to the Na⁺, K⁺-ATPase.

Nielsen HN, Spontarelli K, Holm R, Andersen JP, Einholm AP, Artigas P, Vilsen B. Nielsen HN, et al. Among authors: einholm ap. Sci Rep. 2019 Sep 16;9(1):13344. doi: 10.1038/s41598-019-50009-2. Sci Rep. 2019. PMID: 31527711 Free PMC article.

8

Importance of transmembrane segment M1 of the sarcoplasmic reticulum Ca2+-ATPase in Ca2+ occlusion and phosphoenzyme processing.

Einholm AP, Vilsen B, Andersen JP. Einholm AP, et al. J Biol Chem. 2004 Apr 16;279(16):15888-96. doi: 10.1074/jbc.M400158200. Epub 2004 Jan 30. J Biol Chem. 2004. PMID: 14754883 Free article.

9

Mutation of Gly-94 in transmembrane segment M1 of Na+,K+-ATPase interferes with Na+ and K+ binding in E2P conformation.

Einholm AP, Toustrup-Jensen M, Andersen JP, Vilsen B. Einholm AP, et al. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11254-9. doi: 10.1073/pnas.0501201102. Epub 2005 Jul 27. Proc Natl Acad Sci U S A. 2005. PMID: 16049100 Free PMC article.

10

Importance of Leu99 in transmembrane segment M1 of the Na+, K+ -ATPase in the binding and occlusion of K+.

Einholm AP, Andersen JP, Vilsen B. Einholm AP, et al. J Biol Chem. 2007 Aug 17;282(33):23854-66. doi: 10.1074/jbc.M702259200. Epub 2007 Jun 6. J Biol Chem. 2007. PMID: 17553789 Free article.

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