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281 results

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Page 1
A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways.
Jones CI, Bray S, Garner SF, Stephens J, de Bono B, Angenent WG, Bentley D, Burns P, Coffey A, Deloukas P, Earthrowl M, Farndale RW, Hoylaerts MF, Koch K, Rankin A, Rice CM, Rogers J, Samani NJ, Steward M, Walker A, Watkins NA, Akkerman JW, Dudbridge F, Goodall AH, Ouwehand WH; Bloodomics Consortium. Jones CI, et al. Among authors: hoylaerts mf. Blood. 2009 Aug 13;114(7):1405-16. doi: 10.1182/blood-2009-02-202614. Epub 2009 May 8. Blood. 2009. PMID: 19429868 Free article.
A novel mechanism of sustained platelet αIIbβ3 activation via PEAR1.
Kauskot A, Di Michele M, Loyen S, Freson K, Verhamme P, Hoylaerts MF. Kauskot A, et al. Among authors: hoylaerts mf. Blood. 2012 Apr 26;119(17):4056-65. doi: 10.1182/blood-2011-11-392787. Epub 2012 Feb 27. Blood. 2012. PMID: 22371881 Free article.
Allele-specific DNA methylation reinforces PEAR1 enhancer activity.
Izzi B, Pistoni M, Cludts K, Akkor P, Lambrechts D, Verfaillie C, Verhamme P, Freson K, Hoylaerts MF. Izzi B, et al. Among authors: hoylaerts mf. Blood. 2016 Aug 18;128(7):1003-12. doi: 10.1182/blood-2015-11-682153. Epub 2016 Jun 16. Blood. 2016. PMID: 27313330 Free article.
Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα.
Kardeby C, Fälker K, Haining EJ, Criel M, Lindkvist M, Barroso R, Påhlsson P, Ljungberg LU, Tengdelius M, Rainger GE, Watson S, Eble JA, Hoylaerts MF, Emsley J, Konradsson P, Watson SP, Sun Y, Grenegård M. Kardeby C, et al. Among authors: hoylaerts mf. Blood Adv. 2019 Feb 12;3(3):275-287. doi: 10.1182/bloodadvances.2018024950. Blood Adv. 2019. PMID: 30700416 Free PMC article.
PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway.
Kauskot A, Vandenbriele C, Louwette S, Gijsbers R, Tousseyn T, Freson K, Verhamme P, Hoylaerts MF. Kauskot A, et al. Among authors: hoylaerts mf. Blood. 2013 Jun 27;121(26):5208-17. doi: 10.1182/blood-2012-10-462887. Epub 2013 May 10. Blood. 2013. PMID: 23667054 Free article.
Absence of Pear1 does not affect murine platelet function in vivo.
Criel M, Izzi B, Vandenbriele C, Liesenborghs L, Van Kerckhoven S, Lox M, Cludts K, Jones EA, Vanassche T, Verhamme P, Hoylaerts M. Criel M, et al. Thromb Res. 2016 Oct;146:76-83. doi: 10.1016/j.thromres.2016.08.026. Epub 2016 Aug 26. Thromb Res. 2016. PMID: 27614188
281 results