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International Life Sciences Institute (Health and Environmental Sciences Institute, HESI) initiative on moving towards better predictors of drug-induced torsades de pointes.
Bass AS, Darpo B, Breidenbach A, Bruse K, Feldman HS, Garnes D, Hammond T, Haverkamp W, January C, Koerner J, Lawrence C, Leishman D, Roden D, Valentin JP, Vos MA, Zhou YY, Karluss T, Sager P. Bass AS, et al. Among authors: koerner j. Br J Pharmacol. 2008 Aug;154(7):1491-501. doi: 10.1038/bjp.2008.279. Br J Pharmacol. 2008. PMID: 18663380 Free PMC article.
The Diplomate in Safety Pharmacology (DSP) certification scheme.
Authier S, Curtis MJ, Soloviev M, Redfern WS, Kallman MJ, Hamlin RL, Leishman DJ, Valentin JP, Koerner JE, Vargas HM, Botchway A, Correll K, Pugsley MK. Authier S, et al. Among authors: koerner je. J Pharmacol Toxicol Methods. 2015 Sep-Oct;75:1-4. doi: 10.1016/j.vascn.2015.04.008. Epub 2015 May 8. J Pharmacol Toxicol Methods. 2015. PMID: 25959882
Proarrhythmia liability assessment and the comprehensive in vitro Proarrhythmia Assay (CiPA): An industry survey on current practice.
Authier S, Pugsley MK, Koerner JE, Fermini B, Redfern WS, Valentin JP, Vargas HM, Leishman DJ, Correll K, Curtis MJ. Authier S, et al. Among authors: koerner je. J Pharmacol Toxicol Methods. 2017 Jul;86:34-43. doi: 10.1016/j.vascn.2017.02.021. Epub 2017 Feb 20. J Pharmacol Toxicol Methods. 2017. PMID: 28223123 Free article.
A Proof-of-Concept Evaluation of JTPc and Tp-Tec as Proarrhythmia Biomarkers in Preclinical Species: A Retrospective Analysis by an HESI-Sponsored Consortium.
Boulay E, Abernathy MM, Chui R, Friedrichs GS, Gendron-Parra N, Greiter-Wilke A, Guillon JM, Koerner JE, Menard A, Steidl-Nichols J, Pierson J, Pugsley MK, Rossman EI, Strauss D, Troncy E, Valentin JP, Wisialowski T, Authier S. Boulay E, et al. Among authors: koerner je. Int J Toxicol. 2019 Jan/Feb;38(1):23-32. doi: 10.1177/1091581818813601. Epub 2018 Dec 19. Int J Toxicol. 2019. PMID: 30567462
An Industry Survey With Focus on Cardiovascular Safety Pharmacology Study Design and Data Interpretation.
Authier S, Abernathy MM, Correll K, Chui RW, Dalton J, Foley CM, Friedrichs GS, Koerner JE, Kallman MJ, Pannirselvam M, Redfern WS, Urmaliya V, Valentin JP, Wisialowski T, Zabka TS, Pugsley MK. Authier S, et al. Among authors: koerner je. Int J Toxicol. 2020 Jul/Aug;39(4):274-293. doi: 10.1177/1091581820921338. Epub 2020 May 14. Int J Toxicol. 2020. PMID: 32406289
280 results