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A reduction in Pten tumor suppressor activity promotes ErbB-2-induced mouse prostate adenocarcinoma formation through the activation of signaling cascades downstream of PDK1.
Rodriguez OC, Lai EW, Vissapragada S, Cromelin C, Avetian M, Salinas P, Ramos H, Kallakury B, Casimiro M, Lisanti MP, Tanowitz HB, Pacak K, Glazer RI, Avantaggiati M, Albanese C. Rodriguez OC, et al. Among authors: casimiro m. Am J Pathol. 2009 Jun;174(6):2051-60. doi: 10.2353/ajpath.2009.080859. Epub 2009 May 14. Am J Pathol. 2009. PMID: 19443706 Free PMC article.
Contrast-enhanced in vivo imaging of breast and prostate cancer cells by MRI.
Rodriguez O, Fricke S, Chien C, Dettin L, VanMeter J, Shapiro E, Dai HN, Casimiro M, Ileva L, Dagata J, Johnson MD, Lisanti MP, Koretsky A, Albanese C. Rodriguez O, et al. Among authors: casimiro m. Cell Cycle. 2006 Jan;5(1):113-9. doi: 10.4161/cc.5.1.2295. Epub 2006 Jan 4. Cell Cycle. 2006. PMID: 16340310
ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo.
Casimiro M, Rodriguez O, Pootrakul L, Aventian M, Lushina N, Cromelin C, Ferzli G, Johnson K, Fricke S, Diba F, Kallakury B, Ohanyerenwa C, Chen M, Ostrowski M, Hung MC, Rabbani SA, Datar R, Cote R, Pestell R, Albanese C. Casimiro M, et al. Cancer Res. 2007 May 1;67(9):4364-72. doi: 10.1158/0008-5472.CAN-06-1898. Cancer Res. 2007. PMID: 17483350
Inhibition of cyclin D1 gene transcription by Brg-1.
Rao M, Casimiro MC, Lisanti MP, D'Amico M, Wang C, Shirley LA, Leader JE, Liu M, Stallcup M, Engel DA, Murphy DJ, Pestell RG. Rao M, et al. Among authors: casimiro mc. Cell Cycle. 2008 Mar 1;7(5):647-55. doi: 10.4161/cc.7.5.5446. Epub 2007 Dec 12. Cell Cycle. 2008. PMID: 18239461
Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy.
Mercier I, Casimiro MC, Wang C, Rosenberg AL, Quong J, Minkeu A, Allen KG, Danilo C, Sotgia F, Bonuccelli G, Jasmin JF, Xu H, Bosco E, Aronow B, Witkiewicz A, Pestell RG, Knudsen ES, Lisanti MP. Mercier I, et al. Cancer Biol Ther. 2008 Aug;7(8):1212-25. doi: 10.4161/cbt.7.8.6220. Epub 2008 Aug 30. Cancer Biol Ther. 2008. PMID: 18458534 Free PMC article.
Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation.
Sotgia F, Casimiro MC, Bonuccelli G, Liu M, Whitaker-Menezes D, Er O, Daumer KM, Mercier I, Witkiewicz AK, Minetti C, Capozza F, Gormley M, Quong AA, Rui H, Frank PG, Milliman JN, Knudsen ES, Zhou J, Wang C, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: casimiro mc. Am J Pathol. 2009 Feb;174(2):613-29. doi: 10.2353/ajpath.2009.080653. Am J Pathol. 2009. PMID: 19164602 Free PMC article.
Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
Sotgia F, Del Galdo F, Casimiro MC, Bonuccelli G, Mercier I, Whitaker-Menezes D, Daumer KM, Zhou J, Wang C, Katiyar S, Xu H, Bosco E, Quong AA, Aronow B, Witkiewicz AK, Minetti C, Frank PG, Jimenez SA, Knudsen ES, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: casimiro mc. Am J Pathol. 2009 Mar;174(3):746-61. doi: 10.2353/ajpath.2009.080658. Am J Pathol. 2009. PMID: 19234134 Free PMC article.
Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions.
Mercier I, Casimiro MC, Zhou J, Wang C, Plymire C, Bryant KG, Daumer KM, Sotgia F, Bonuccelli G, Witkiewicz AK, Lin J, Tran TH, Milliman J, Frank PG, Jasmin JF, Rui H, Pestell RG, Lisanti MP. Mercier I, et al. Among authors: casimiro mc. Am J Pathol. 2009 Apr;174(4):1172-90. doi: 10.2353/ajpath.2009.080882. Am J Pathol. 2009. PMID: 19342371 Free PMC article.
115 results