Zabka TS - Search Results

1

In vitro to in vivo concordance of a high throughput assay of bone marrow toxicity across a diverse set of drug candidates.

Olaharski AJ, Uppal H, Cooper M, Platz S, Zabka TS, Kolaja KL. Olaharski AJ, et al. Among authors: zabka ts. Toxicol Lett. 2009 Jul 24;188(2):98-103. doi: 10.1016/j.toxlet.2009.03.012. Epub 2009 Mar 25. Toxicol Lett. 2009. PMID: 19446241

2

Modeling bone marrow toxicity using kinase structural motifs and the inhibition profiles of small molecular kinase inhibitors.

Olaharski AJ, Bitter H, Gonzaludo N, Kondru R, Goldstein DM, Zabka TS, Lin H, Singer T, Kolaja K. Olaharski AJ, et al. Among authors: zabka ts. Toxicol Sci. 2010 Nov;118(1):266-75. doi: 10.1093/toxsci/kfq258. Epub 2010 Sep 1. Toxicol Sci. 2010. PMID: 20810542

3

Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid.

Tarrant JM, Dhawan P, Singh J, Zabka TS, Clarke E, DosSantos G, Dragovich PS, Sampath D, Lin T, McCray B, La N, Nguyen T, Kauss A, Dambach D, Misner DL, Diaz D, Uppal H. Tarrant JM, et al. Among authors: zabka ts. Toxicol Mech Methods. 2015 Mar;25(3):201-11. doi: 10.3109/15376516.2015.1014080. Epub 2015 Apr 20. Toxicol Mech Methods. 2015. PMID: 25894564

4

Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.

Zabka TS, Singh J, Dhawan P, Liederer BM, Oeh J, Kauss MA, Xiao Y, Zak M, Lin T, McCray B, La N, Nguyen T, Beyer J, Farman C, Uppal H, Dragovich PS, O'Brien T, Sampath D, Misner DL. Zabka TS, et al. Toxicol Sci. 2015 Mar;144(1):163-72. doi: 10.1093/toxsci/kfu268. Epub 2014 Dec 11. Toxicol Sci. 2015. PMID: 25505128

5

Characterization of xenobiotic-induced hepatocellular enzyme induction in rats: anticipated thyroid effects and unique pituitary gland findings.

Zabka TS, Fielden MR, Garrido R, Tao J, Fretland AJ, Fretland JL, Albassam MA, Singer T, Kolaja KL. Zabka TS, et al. Toxicol Pathol. 2011 Jun;39(4):664-77. doi: 10.1177/0192623311406934. Epub 2011 May 5. Toxicol Pathol. 2011. PMID: 21551028

6

Cardiotoxicity Associated with Nicotinamide Phosphoribosyltransferase Inhibitors in Rodents and in Rat and Human-Derived Cells Lines.

Misner DL, Kauss MA, Singh J, Uppal H, Bruening-Wright A, Liederer BM, Lin T, McCray B, La N, Nguyen T, Sampath D, Dragovich PS, O'Brien T, Zabka TS. Misner DL, et al. Among authors: zabka ts. Cardiovasc Toxicol. 2017 Jul;17(3):307-318. doi: 10.1007/s12012-016-9387-6. Cardiovasc Toxicol. 2017. PMID: 27783203

7

An Industry Survey With Focus on Cardiovascular Safety Pharmacology Study Design and Data Interpretation.

Authier S, Abernathy MM, Correll K, Chui RW, Dalton J, Foley CM, Friedrichs GS, Koerner JE, Kallman MJ, Pannirselvam M, Redfern WS, Urmaliya V, Valentin JP, Wisialowski T, Zabka TS, Pugsley MK. Authier S, et al. Among authors: zabka ts. Int J Toxicol. 2020 Jul/Aug;39(4):274-293. doi: 10.1177/1091581820921338. Epub 2020 May 14. Int J Toxicol. 2020. PMID: 32406289

8

The use of emerging safety biomarkers in nonclinical and clinical safety assessment - The current and future state: An IQ DruSafe industry survey.

Zabka TS, Burkhardt J, Reagan WJ, Gautier JC, Glaab WE, Guffroy M, Harding J, Brees D, McDuffie E, Ramaiah L, Schultze AE, Smith JD, Wolfreys A, Dalmas DA. Zabka TS, et al. Regul Toxicol Pharmacol. 2021 Mar;120:104857. doi: 10.1016/j.yrtph.2020.104857. Epub 2020 Dec 31. Regul Toxicol Pharmacol. 2021. PMID: 33387566 Free article.

9

Evaluation of the Relative Performance of Drug-Induced Skeletal Muscle Injury Biomarkers in Rats.

Burch PM, Greg Hall D, Walker EG, Bracken W, Giovanelli R, Goldstein R, Higgs RE, King NM, Lane P, Sauer JM, Michna L, Muniappa N, Pritt ML, Vlasakova K, Watson DE, Wescott D, Zabka TS, Glaab WE. Burch PM, et al. Among authors: zabka ts. Toxicol Sci. 2016 Mar;150(1):247-56. doi: 10.1093/toxsci/kfv328. Epub 2015 Dec 31. Toxicol Sci. 2016. PMID: 26721300

10

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer.

Sampath D, Zabka TS, Misner DL, O'Brien T, Dragovich PS. Sampath D, et al. Among authors: zabka ts. Pharmacol Ther. 2015 Jul;151:16-31. doi: 10.1016/j.pharmthera.2015.02.004. Epub 2015 Feb 21. Pharmacol Ther. 2015. PMID: 25709099 Review.

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