A dual-targeting PDGFRbeta/VEGF-A molecule assembled from stable antibody fragments demonstrates anti-angiogenic activity in vitro and in vivo.
Mabry R, Gilbertson DG, Frank A, Vu T, Ardourel D, Ostrander C, Stevens B, Julien S, Franke S, Meengs B, Brody J, Presnell S, Hamacher NB, Lantry M, Wolf A, Bukowski T, Rosler R, Yen C, Anderson-Haley M, Brasel K, Pan Q, Franklin H, Thompson P, Dodds M, Underwood S, Peterson S, Sivakumar PV, Snavely M.
Mabry R, et al. Among authors: underwood s.
MAbs. 2010 Jan-Feb;2(1):20-34. doi: 10.4161/mabs.2.1.10498. Epub 2010 Jan 2.
MAbs. 2010.
PMID: 20065654
Free PMC article.