Spear PG - Search Results

1

Differential effects on cell fusion activity of mutations in herpes simplex virus 1 glycoprotein B (gB) dependent on whether a gD receptor or a gB receptor is overexpressed.

Fan Q, Lin E, Satoh T, Arase H, Spear PG. Fan Q, et al. Among authors: spear pg. J Virol. 2009 Aug;83(15):7384-90. doi: 10.1128/JVI.00087-09. Epub 2009 May 20. J Virol. 2009. PMID: 19457990 Free PMC article.

2

Random linker-insertion mutagenesis to identify functional domains of herpes simplex virus type 1 glycoprotein B.

Lin E, Spear PG. Lin E, et al. Among authors: spear pg. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13140-5. doi: 10.1073/pnas.0705926104. Epub 2007 Jul 31. Proc Natl Acad Sci U S A. 2007. PMID: 17666526 Free PMC article.

3

Insertional mutations in herpes simplex virus type 1 gL identify functional domains for association with gH and for membrane fusion.

Fan Q, Lin E, Spear PG. Fan Q, et al. Among authors: spear pg. J Virol. 2009 Nov;83(22):11607-15. doi: 10.1128/JVI.01369-09. Epub 2009 Sep 2. J Virol. 2009. PMID: 19726507 Free PMC article.

4

Binding of herpes simplex virus glycoprotein B (gB) to paired immunoglobulin-like type 2 receptor alpha depends on specific sialylated O-linked glycans on gB.

Wang J, Fan Q, Satoh T, Arii J, Lanier LL, Spear PG, Kawaguchi Y, Arase H. Wang J, et al. Among authors: spear pg. J Virol. 2009 Dec;83(24):13042-5. doi: 10.1128/JVI.00792-09. Epub 2009 Oct 7. J Virol. 2009. PMID: 19812165 Free PMC article.

5

Insertion mutations in herpes simplex virus 1 glycoprotein H reduce cell surface expression, slow the rate of cell fusion, or abrogate functions in cell fusion and viral entry.

Jackson JO, Lin E, Spear PG, Longnecker R. Jackson JO, et al. Among authors: spear pg. J Virol. 2010 Feb;84(4):2038-46. doi: 10.1128/JVI.02215-09. Epub 2009 Dec 9. J Virol. 2010. PMID: 20007280 Free PMC article.

6

Disruption of adherens junctions liberates nectin-1 to serve as receptor for herpes simplex virus and pseudorabies virus entry.

Yoon M, Spear PG. Yoon M, et al. Among authors: spear pg. J Virol. 2002 Jul;76(14):7203-8. doi: 10.1128/jvi.76.14.7203-7208.2002. J Virol. 2002. PMID: 12072519 Free PMC article.

7

Amino acid substitutions in the V domain of nectin-1 (HveC) that impair entry activity for herpes simplex virus types 1 and 2 but not for Pseudorabies virus or bovine herpesvirus 1.

Martinez WM, Spear PG. Martinez WM, et al. Among authors: spear pg. J Virol. 2002 Jul;76(14):7255-62. doi: 10.1128/jvi.76.14.7255-7262.2002. J Virol. 2002. PMID: 12072525 Free PMC article.

8

Mutations in the N termini of herpes simplex virus type 1 and 2 gDs alter functional interactions with the entry/fusion receptors HVEM, nectin-2, and 3-O-sulfated heparan sulfate but not with nectin-1.

Yoon M, Zago A, Shukla D, Spear PG. Yoon M, et al. Among authors: spear pg. J Virol. 2003 Sep;77(17):9221-31. doi: 10.1128/jvi.77.17.9221-9231.2003. J Virol. 2003. PMID: 12915538 Free PMC article.

9

Differences in the N termini of herpes simplex virus type 1 and 2 gDs that influence functional interactions with the human entry receptor Nectin-2 and an entry receptor expressed in Chinese hamster ovary cells.

Zago A, Spear PG. Zago A, et al. Among authors: spear pg. J Virol. 2003 Sep;77(17):9695-9. doi: 10.1128/jvi.77.17.9695-9699.2003. J Virol. 2003. PMID: 12915581 Free PMC article.

10

Effects of linker-insertion mutations in herpes simplex virus 1 gD on glycoprotein-induced fusion with cells expressing HVEM or nectin-1.

Jogger CR, Montgomery RI, Spear PG. Jogger CR, et al. Among authors: spear pg. Virology. 2004 Jan 5;318(1):318-26. doi: 10.1016/j.virol.2003.10.004. Virology. 2004. PMID: 14972557 Free article.

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