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Page 1
Chromosomal instability determines taxane response.
Swanton C, Nicke B, Schuett M, Eklund AC, Ng C, Li Q, Hardcastle T, Lee A, Roy R, East P, Kschischo M, Endesfelder D, Wylie P, Kim SN, Chen JG, Howell M, Ried T, Habermann JK, Auer G, Brenton JD, Szallasi Z, Downward J. Swanton C, et al. Among authors: lee a. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8671-6. doi: 10.1073/pnas.0811835106. Epub 2009 May 19. Proc Natl Acad Sci U S A. 2009. PMID: 19458043 Free PMC article.
Chromosomal instability confers intrinsic multidrug resistance.
Lee AJ, Endesfelder D, Rowan AJ, Walther A, Birkbak NJ, Futreal PA, Downward J, Szallasi Z, Tomlinson IP, Howell M, Kschischo M, Swanton C. Lee AJ, et al. Cancer Res. 2011 Mar 1;71(5):1858-70. doi: 10.1158/0008-5472.CAN-10-3604. Cancer Res. 2011. PMID: 21363922 Free PMC article.
CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction.
Lee AJ, Roylance R, Sander J, Gorman P, Endesfelder D, Kschischo M, Jones NP, East P, Nicke B, Spassieva S, Obeid LM, Birkbak NJ, Szallasi Z, McKnight NC, Rowan AJ, Speirs V, Hanby AM, Downward J, Tooze SA, Swanton C. Lee AJ, et al. J Pathol. 2012 Feb;226(3):482-94. doi: 10.1002/path.2998. Epub 2011 Oct 19. J Pathol. 2012. PMID: 21953249
Basic Science and Pathogenesis.
Wang TC, Archer DB, Ali M, Wu Y, Mormino E, Buckley RF, Lee AJ, Saykin AJ, De Jager PL, Schneider JA, Bennett DA, Barnes LL, Vardarajan BN, Mayeux R, Kunkle BW, Bush WS, Keene CD, Seshadri S, Sperling RA, Vemuri P, Ramanan VK, Schellenberg GD, Huentelman MJ, Hamilton-Nelson KL, Pericak-Vance MA, Goate AM, Haines JL, Montine TJ, Beecham GW Jr, Cruchaga C, Hohman TJ, Dumitrescu LC; ADNI, Knight Alzheimer Disease Research Center (Knight ADRC), the Dominantly Inherited Alzheimer Network (DIAN), ADNI‐DOD, the Australian Imaging Biomarkers, Lifestyle (AIBL) Study, A4 Study Team, Alzheimer’s Disease Sequencing Project (ADSP). Wang TC, et al. Among authors: lee aj. Alzheimers Dement. 2024 Dec;20 Suppl 1:e090566. doi: 10.1002/alz.090566. Alzheimers Dement. 2024. PMID: 39751611
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