Kjer-Nielsen L - Search Results

1

Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor.

Beddoe T, Chen Z, Clements CS, Ely LK, Bushell SR, Vivian JP, Kjer-Nielsen L, Pang SS, Dunstone MA, Liu YC, Macdonald WA, Perugini MA, Wilce MC, Burrows SR, Purcell AW, Tiganis T, Bottomley SP, McCluskey J, Rossjohn J. Beddoe T, et al. Immunity. 2009 Jun 19;30(6):777-88. doi: 10.1016/j.immuni.2009.03.018. Epub 2009 May 21. Immunity. 2009. PMID: 19464197 Free article.

2

Impaired expression of chimaeric major histocompatibility complex transgenes associated with plasmid sequences.

Kjer-Nielsen L, Holmberg K, Perera JD, McCluskey J. Kjer-Nielsen L, et al. Transgenic Res. 1992 Jul;1(4):182-7. doi: 10.1007/BF02522537. Transgenic Res. 1992. PMID: 1301211

3

Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme.

Brooks A, Hartley S, Kjer-Nielsen L, Perera J, Goodnow CC, Basten A, McCluskey J. Brooks A, et al. Proc Natl Acad Sci U S A. 1991 Apr 15;88(8):3290-4. doi: 10.1073/pnas.88.8.3290. Proc Natl Acad Sci U S A. 1991. PMID: 1707537 Free PMC article.

4

The extracellular domains of MHC class II molecules determine their processing requirements for antigen presentation.

Kjer-Nielsen L, Perera JD, Boyd LF, Margulies DH, McCluskey J. Kjer-Nielsen L, et al. J Immunol. 1990 Apr 15;144(8):2915-24. J Immunol. 1990. PMID: 1969876

5

Structure function analysis of in vitro mutated CD4 and major histocompatibility complex class II gene products.

McCluskey J, Kjer-Nielsen L, Blok R. McCluskey J, et al. J Autoimmun. 1990 Apr;3 Suppl 1:91-6. doi: 10.1016/s0896-8411(09)90016-6. J Autoimmun. 1990. PMID: 2340062

6

The role of major histocompatibility molecules in antigen-specific immune responses.

McCluskey J, Blok R, Kjer-Nielsen L. McCluskey J, et al. Transplant Proc. 1989 Feb;21(1 Pt 1):591-4. Transplant Proc. 1989. PMID: 2495622 Review. No abstract available.

7

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex.

Macdonald W, Williams DS, Clements CS, Gorman JJ, Kjer-Nielsen L, Brooks AG, McCluskey J, Rossjohn J, Purcell AW. Macdonald W, et al. FEBS Lett. 2002 Sep 11;527(1-3):27-32. doi: 10.1016/s0014-5793(02)03149-6. FEBS Lett. 2002. PMID: 12220628 Free article.

8

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, Fontes MR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. J Immunol. 2002 Nov 1;169(9):5153-60. doi: 10.4049/jimmunol.169.9.5153. J Immunol. 2002. PMID: 12391232

9

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Structure. 2002 Nov;10(11):1521-32. doi: 10.1016/s0969-2126(02)00878-x. Structure. 2002. PMID: 12429093 Free article.

10

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state.

Clements CS, Kjer-Nielsen L, MacDonald WA, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Clements CS, et al. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2131-4. doi: 10.1107/s0907444902015482. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454477

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