Fowler JD - Search Results

1

Probing conformational changes of human DNA polymerase lambda using mass spectrometry-based protein footprinting.

Fowler JD, Brown JA, Kvaratskhelia M, Suo Z. Fowler JD, et al. J Mol Biol. 2009 Jul 17;390(3):368-79. doi: 10.1016/j.jmb.2009.05.037. Epub 2009 May 23. J Mol Biol. 2009. PMID: 19467241 Free PMC article.

2

Biochemical, structural, and physiological characterization of terminal deoxynucleotidyl transferase.

Fowler JD, Suo Z. Fowler JD, et al. Chem Rev. 2006 Jun;106(6):2092-110. doi: 10.1021/cr040445w. Chem Rev. 2006. PMID: 16771444 Review. No abstract available.

3

Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta.

Brown JA, Duym WW, Fowler JD, Suo Z. Brown JA, et al. Among authors: fowler jd. J Mol Biol. 2007 Apr 13;367(5):1258-69. doi: 10.1016/j.jmb.2007.01.069. Epub 2007 Feb 3. J Mol Biol. 2007. PMID: 17321545

4

Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase.

Fowler JD, Brown JA, Johnson KA, Suo Z. Fowler JD, et al. J Biol Chem. 2008 May 30;283(22):15339-48. doi: 10.1074/jbc.M800310200. Epub 2008 Mar 31. J Biol Chem. 2008. PMID: 18378680 Free PMC article.

5

Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase.

Sherrer SM, Brown JA, Pack LR, Jasti VP, Fowler JD, Basu AK, Suo Z. Sherrer SM, et al. Among authors: fowler jd. J Biol Chem. 2009 Mar 6;284(10):6379-88. doi: 10.1074/jbc.M808161200. Epub 2009 Jan 5. J Biol Chem. 2009. PMID: 19124465 Free PMC article.

6

A novel mechanism of sugar selection utilized by a human X-family DNA polymerase.

Brown JA, Fiala KA, Fowler JD, Sherrer SM, Newmister SA, Duym WW, Suo Z. Brown JA, et al. Among authors: fowler jd. J Mol Biol. 2010 Jan 15;395(2):282-90. doi: 10.1016/j.jmb.2009.11.003. Epub 2009 Nov 6. J Mol Biol. 2010. PMID: 19900463 Free PMC article.

7

Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase.

Brown JA, Fowler JD, Suo Z. Brown JA, et al. Among authors: fowler jd. Biochemistry. 2010 Jul 6;49(26):5504-10. doi: 10.1021/bi100433x. Biochemistry. 2010. PMID: 20518555 Free PMC article.

8

Backbone assignment of the catalytic core of a Y-family DNA polymerase.

Ma D, Fowler JD, Yuan C, Suo Z. Ma D, et al. Among authors: fowler jd. Biomol NMR Assign. 2010 Oct;4(2):207-9. doi: 10.1007/s12104-010-9244-7. Epub 2010 Jun 29. Biomol NMR Assign. 2010. PMID: 20582735

9

Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases.

Sherrer SM, Fiala KA, Fowler JD, Newmister SA, Pryor JM, Suo Z. Sherrer SM, et al. Among authors: fowler jd. Nucleic Acids Res. 2011 Jan;39(2):609-22. doi: 10.1093/nar/gkq719. Epub 2010 Sep 15. Nucleic Acids Res. 2011. PMID: 20846959 Free PMC article.

10

Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λ.

Brown JA, Pack LR, Sherrer SM, Kshetry AK, Newmister SA, Fowler JD, Taylor JS, Suo Z. Brown JA, et al. Among authors: fowler jd. J Mol Biol. 2010 Nov 5;403(4):505-15. doi: 10.1016/j.jmb.2010.09.014. Epub 2010 Sep 21. J Mol Biol. 2010. PMID: 20851705 Free PMC article.

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