Brody JR - Search Results

1

The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase.

Costantino CL, Witkiewicz AK, Kuwano Y, Cozzitorto JA, Kennedy EP, Dasgupta A, Keen JC, Yeo CJ, Gorospe M, Brody JR. Costantino CL, et al. Among authors: brody jr. Cancer Res. 2009 Jun 1;69(11):4567-72. doi: 10.1158/0008-5472.CAN-09-0371. Cancer Res. 2009. PMID: 19487279 Free PMC article.

2

Targeted disruption of FANCC and FANCG in human cancer provides a preclinical model for specific therapeutic options.

Gallmeier E, Calhoun ES, Rago C, Brody JR, Cunningham SC, Hucl T, Gorospe M, Kohli M, Lengauer C, Kern SE. Gallmeier E, et al. Among authors: brody jr. Gastroenterology. 2006 Jun;130(7):2145-54. doi: 10.1053/j.gastro.2006.03.016. Gastroenterology. 2006. PMID: 16762635

3

Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: a model for patient classification to aid fluoropyrimidine therapy.

Brody JR, Hucl T, Gallmeier E, Winter JM, Kern SE, Murphy KM. Brody JR, et al. Cancer Res. 2006 Oct 1;66(19):9369-73. doi: 10.1158/0008-5472.CAN-06-2165. Cancer Res. 2006. PMID: 17018589

4

Reduction of pp32 expression in poorly differentiated pancreatic ductal adenocarcinomas and intraductal papillary mucinous neoplasms with moderate dysplasia.

Brody JR, Witkiewicz A, Williams TK, Kadkol SS, Cozzitorto J, Durkan B, Pasternack GR, Yeo CJ. Brody JR, et al. Mod Pathol. 2007 Dec;20(12):1238-44. doi: 10.1038/modpathol.3800974. Epub 2007 Sep 28. Mod Pathol. 2007. PMID: 17906614 Free article.

5

High cancer-specific expression of mesothelin (MSLN) is attributable to an upstream enhancer containing a transcription enhancer factor dependent MCAT motif.

Hucl T, Brody JR, Gallmeier E, Iacobuzio-Donahue CA, Farrance IK, Kern SE. Hucl T, et al. Among authors: brody jr. Cancer Res. 2007 Oct 1;67(19):9055-65. doi: 10.1158/0008-5472.CAN-07-0474. Cancer Res. 2007. PMID: 17909009

6

Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil. Is it time to move forward?

Showalter SL, Showalter TN, Witkiewicz A, Havens R, Kennedy EP, Hucl T, Kern SE, Yeo CJ, Brody JR. Showalter SL, et al. Among authors: brody jr. Cancer Biol Ther. 2008 Jul;7(7):986-94. doi: 10.4161/cbt.7.7.6181. Epub 2008 Apr 21. Cancer Biol Ther. 2008. PMID: 18443433 Free PMC article. Review.

7

Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detection.

Witkiewicz A, Williams TK, Cozzitorto J, Durkan B, Showalter SL, Yeo CJ, Brody JR. Witkiewicz A, et al. Among authors: brody jr. J Am Coll Surg. 2008 May;206(5):849-54; discussion 854-6. doi: 10.1016/j.jamcollsurg.2007.12.014. Epub 2008 Mar 4. J Am Coll Surg. 2008. PMID: 18471709

8

A syngeneic variance library for functional annotation of human variation: application to BRCA2.

Hucl T, Rago C, Gallmeier E, Brody JR, Gorospe M, Kern SE. Hucl T, et al. Among authors: brody jr. Cancer Res. 2008 Jul 1;68(13):5023-30. doi: 10.1158/0008-5472.CAN-07-6189. Cancer Res. 2008. PMID: 18593900 Free PMC article.

9

Does this band make sense? Limits to expression based cancer studies.

Williams TK, Yeo CJ, Brody J. Williams TK, et al. Cancer Lett. 2008 Nov 18;271(1):81-4. doi: 10.1016/j.canlet.2008.05.033. Epub 2008 Jul 7. Cancer Lett. 2008. PMID: 18602748

10

Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells.

Hostetter C, Licata LA, Witkiewicz A, Costantino CL, Yeo CJ, Brody JR, Keen JC. Hostetter C, et al. Among authors: brody jr. Cancer Biol Ther. 2008 Sep;7(9):1496-506. doi: 10.4161/cbt.7.9.6490. Epub 2008 Sep 23. Cancer Biol Ther. 2008. PMID: 18769129 Free article.

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